Results 61 to 70 of about 26,141 (311)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Contextual information retrieval based on algorithmic information theory and statistical outlier detection [PDF]

open access: yes2008 IEEE Information Theory Workshop, 2007
This work presents an Information Retrieval technique based on algorithmic information theory (using the normalized compression distance), statistical data outlier detection, and a novel database structure.
Rafael Martínez   +3 more
semanticscholar   +1 more source

A Robust and Effective Smart-Card-Based Remote User Authentication Mechanism Using Hash Function

open access: yesThe Scientific World Journal, 2014
In a remote user authentication scheme, a remote server verifies whether a login user is genuine and trustworthy, and also for mutual authentication purpose a login user validates whether the remote server is genuine and trustworthy.
Ashok Kumar Das   +2 more
doaj   +1 more source

Healthcare 5.0 Security Framework: Applications, Issues and Future Research Directions

open access: yesIEEE Access, 2022
Healthcare 5.0 is a system that can be deployed to provide various healthcare services. It does these services by utilising a new generation of information technologies, such as Internet of Things (IoT), Artificial Intelligence (AI), Big data analytics ...
Mohammad Wazid   +3 more
doaj   +1 more source

Information Theory and Computational Thermodynamics: Lessons for Biology from Physics

open access: yes, 2012
We survey a few aspects of the thermodynamics of computation, connecting information, thermodynamics, computability and physics. We suggest some lines of research into how information theory and computational thermodynamics can help us arrive at a better
Hector Zenil
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Towards a Unified Theory of Learning and Information

open access: yes, 2020
In this paper, we introduce the notion of “learning capacity” for algorithms that learn from data, which is analogous to the Shannon channel capacity for communication systems.
Ibrahim Alabdulmohsin
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Notions and applications of algorithmic randomness [PDF]

open access: yes, 2013
Algorithmic randomness uses computability theory to define notions of randomness for infinite objects such as infinite binary sequences. The different possible definitions lead to a hierarchy of randomness notions. In this thesis we study this hierarchy,
Vermeeren, Stijn
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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