Results 31 to 40 of about 3,571 (240)
Probabilistic Analysis of Pattern Formation in Monotonic Self-Assembly. [PDF]
PLoS ONE, 2015 Inspired by biological systems, self-assembly aims to construct complex structures. It functions through piece-wise, local interactions among component parts and has the potential to produce novel materials and devices at the nanoscale.
Tyler G Moore +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
A randomized approximate nearest neighbors algorithm [PDF]
Applied and Computational Harmonic Analysis, 2011 We present a randomized algorithm for the approximate nearest neighbor problem in d -dimensional Euclidean space. Given N points { x j } in , the ...
Peter Wilcox, Jones +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
New Journal of Physics, 2016 We postulate a principle stating that the initial condition of a physical system is typically algorithmically independent of the dynamical law. We discuss the implications of this principle and argue that they link thermodynamics and causal inference. On
Dominik Janzing +2 more
doaj +1 more source
A Peer-Reviewed Journal About, 2019 This paper proposes a reconsideration of the aesthetic category of ‘glitch’ and advocates for a more careful theorisation around indexing — in the sense of both locating and naming — errors of a digital kind.
Carleigh Morgan
doaj +1 more source
Multi-robot path planning based on a deep reinforcement learning DQN algorithm
CAAI Transactions on Intelligence Technology, 2020 The unmanned warehouse dispatching system of the ‘goods to people’ model uses a structure mainly based on a handling robot, which saves considerable manpower and improves the efficiency of the warehouse picking operation. However, the optimal performance
Yang Yang, Li Juntao, Peng Lingling
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2015 The complexity or randomness of the laminar-turbulent transition process of an inlet boundary layer in a circular pipe was analyzed by use of Kolmogorov complexity which is a very important measure of the randomness of various events. In the inlet region
Masashi ICHIMIYA +2 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source