Results 31 to 40 of about 243 (214)
A Randomized Algorithm for CCA
We present RandomizedCCA, a randomized algorithm for computing canonical analysis, suitable for large datasets stored either out of core or on a distributed file system. Accurate results can be obtained in as few as two data passes, which is relevant for distributed processing frameworks in which iteration is expensive (e.g., Hadoop). The strategy also
Paul Mineiro, Nikos Karampatziakis
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We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
RANDOMIZED ALGORITHMS FOR MOTIF DETECTION [PDF]
Motivation: Motif detection for DNA sequences has many important applications in biological studies, e.g. locating binding sites regulatory signals, designing genetic probes etc. In this paper, we propose a randomized algorithm, design an improved EM algorithm and combine them to form a software tool. Results: (1) We design a randomized algorithm for
Lusheng Wang 0001, Liang Dong
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A Randomized Algorithm for 3-SAT [PDF]
In this work we propose and analyze a simple randomized algorithm to find a satisfiable assignment for a Boolean formula in conjunctive normal form (CNF) having at most 3 literals in every clause. Given a k-CNF formula phi on n variables, and alpha in{0,1}^n that satisfies phi, a clause of phi is critical if exactly one literal of that clause is ...
Subhas Kumar Ghosh, Janardan Misra
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We postulate a principle stating that the initial condition of a physical system is typically algorithmically independent of the dynamical law. We discuss the implications of this principle and argue that they link thermodynamics and causal inference. On
Dominik Janzing +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Bitslice Masking and Improved Shuffling:
We revisit the popular adage that side-channel countermeasures must be combined to be efficient, and study its application to bitslice masking and shuffling. Our main contributions are twofold. First, we improve this combination: by shuffling the shares
Melissa Azouaoui +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
An introduction to randomized algorithms
The concept of randomization is known to be an extremely important tool for the design of algorithms. Its use often yields better time or space complexity compared with the best deterministic algorithms we know of for the same problem; moreover resulting randomized algorithms are often very simple to understand and implement.
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