Results 31 to 40 of about 22,331 (209)

An Algorithmic Approach to Information and Meaning [PDF]

open access: yes, 2011
I will survey some matters of relevance to a philosophical discussion of information, taking into account developments in algorithmic information theory (AIT).
Zenil, Hector
core   +4 more sources

Lines Missing Every Random Point

open access: yes, 2014
We prove that there is, in every direction in Euclidean space, a line that misses every computably random point. We also prove that there exist, in every direction in Euclidean space, arbitrarily long line segments missing every double exponential time ...
A.S. Besicovitch   +19 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Fourier spectra of measures associated with algorithmically random Brownian motion

open access: yes, 2014
In this paper we study the behaviour at infinity of the Fourier transform of Radon measures supported by the images of fractal sets under an algorithmically random Brownian motion.
Davie, George   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Impossibility of independence amplification in Kolmogorov complexity theory

open access: yes, 2010
The paper studies randomness extraction from sources with bounded independence and the issue of independence amplification of sources, using the framework of Kolmogorov complexity. The dependency of strings $x$ and $y$ is ${\rm dep}(x,y) = \max\{C(x) - C(
A. Rao   +12 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Quantum Algorithmic Integrability: The Metaphor of Polygonal Billiards

open access: yes, 1999
An elementary application of Algorithmic Complexity Theory to the polygonal approximations of curved billiards-integrable and chaotic-unveils the equivalence of this problem to the procedure of quantization of classical systems: the scaling relations for
Mantica, Giorgio
core   +1 more source

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