Results 91 to 100 of about 9,890,926 (378)
Algorithms, Algorithms, Algorithms [PDF]
Computer, 2020 James Bret Michael, Jeffrey Voas
openaire +2 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Combinatorial optimization in networks with Shared Risk Link Groups [PDF]
Discrete Mathematics & Theoretical Computer Science, 2016 The notion of Shared Risk Link Groups (SRLG) captures survivability issues when a set of links of a network may fail simultaneously. The theory of survivable network design relies on basic combinatorial objects that are rather easy to compute in the ...
David Coudert +3 more
doaj +1 more source
Cache-Oblivious VAT-Algorithms [PDF]
, 2014 The VAT-model (virtual address translation model) extends the EM-model (external memory model) and takes the cost of address translation in virtual memories into account. In this model, the cost of a single memory access may be logarithmic in the largest
Jurkiewicz, Tomasz +2 more
core
Packet Transactions: High-level Programming for Line-Rate Switches
, 2016 Many algorithms for congestion control, scheduling, network measurement, active queue management, security, and load balancing require custom processing of packets as they traverse the data plane of a network switch. To run at line rate, these data-plane
Alizadeh, Mohammad +8 more
core +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Analyzing variational quantum landscapes with information content
npj Quantum InformationThe parameters of the quantum circuit in a variational quantum algorithm induce a landscape that contains the relevant information regarding its optimization hardness.
Adrián Pérez-Salinas +2 more
doaj +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source