Results 121 to 130 of about 5,009,966 (344)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Cache-Oblivious VAT-Algorithms [PDF]

open access: yes, 2014
The VAT-model (virtual address translation model) extends the EM-model (external memory model) and takes the cost of address translation in virtual memories into account. In this model, the cost of a single memory access may be logarithmic in the largest
Jurkiewicz, Tomasz   +2 more
core  

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Fast Local Computation Algorithms [PDF]

open access: yes, 2011
For input $x$, let $F(x)$ denote the set of outputs that are the "legal" answers for a computational problem $F$. Suppose $x$ and members of $F(x)$ are so large that there is not time to read them in their entirety.
Rubinfeld, Ronitt   +3 more
core   +3 more sources

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

The color algorithm

open access: yes
The presented material constitutes an integral part of the work entitled "The Formula of Metamorphosis," included in the volume "Metamorphosis." This work analyzes not only fundamental mathematical concepts but also the color palette used in algorithmic formulas.
openaire   +4 more sources

Machines and Algorithms [PDF]

open access: yesProceedings of 34th annual International Symposium on Lattice Field Theory — PoS(LATTICE2016), 2017
I discuss the evolution of computer architectures with a focus on QCD and with reference to the interplay between architecture, engineering, data motion and algorithms. New architectures are discussed and recent performance results are displayed. I also review recent progress in multilevel solver and integation algorithms.
openaire   +3 more sources

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