Results 121 to 130 of about 9,890,926 (378)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Algorithms

open access: yes, 2019
Algorithms To Supports Individual Fairness by Incorporating System Design ...
openaire   +1 more source

Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis

open access: yesJournal of Immunology Research, 2015
Neurodegenerative as well as autoimmune diseases have unclear aetiologies, but an increasing number of evidences report for a combination of genetic and epigenetic alterations that predispose for the development of disease. This review examines the major
Afroza Khanam Irin   +3 more
doaj   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

open access: yesMolecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza   +5 more
wiley   +1 more source

Algorithmic Blending

open access: yesJournal of Approximation Theory, 1993
An algorithm is given by wich one can obtain a 4-sided \(C^ 1\) surface patch. The algorithm can be used to interpolate 4 arbitrary polynomial boundary curves together with corresponding tangent planes. The method presented can be generalized to produce \(C^ K\) surfaces which are piecewise polynomial of degree \(2k+1\) or higher and which interpolate ...
openaire   +2 more sources

Algorithmics of Diffraction [PDF]

open access: yesActa Physica Polonica B Proceedings Supplement, 2019
Diffraction and Low-x 2018 proceedings (Acta Phys. Pol.
openaire   +4 more sources

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

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