Results 41 to 50 of about 7,082,722 (377)

PS4DR: a multimodal workflow for identification and prioritization of drugs based on pathway signatures

open access: yesBMC Bioinformatics, 2020
Background During the last decade, there has been a surge towards computational drug repositioning owing to constantly increasing -omics data in the biomedical research field. While numerous existing methods focus on the integration of heterogeneous data
Mohammad Asif Emon   +3 more
doaj   +1 more source

On Algorithmic Statistics for Space-Bounded Algorithms [PDF]

open access: yesTheory of Computing Systems, 2017
accepted to CSR 2017 ...
Alexey Milovanov   +2 more
openaire   +4 more sources

ADataViewer: exploring semantically harmonized Alzheimer’s disease cohort datasets

open access: yesAlzheimer’s Research & Therapy, 2022
Background Currently, Alzheimer’s disease (AD) cohort datasets are difficult to find and lack across-cohort interoperability, and the actual content of publicly available datasets often only becomes clear to third-party researchers once data access has ...
Yasamin Salimi   +5 more
doaj   +1 more source

PathMe: merging and exploring mechanistic pathway knowledge

open access: yesBMC Bioinformatics, 2019
Background The complexity of representing biological systems is compounded by an ever-expanding body of knowledge emerging from multi-omics experiments.
Daniel Domingo-Fernández   +4 more
doaj   +1 more source

A note on compact and compact circular edge-colorings of graphs [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2008
Graphs and ...
Dariusz Dereniowski, Adam Nadolski
doaj   +1 more source

Approximation algorithms [PDF]

open access: yesProceedings of the National Academy of Sciences, 1997
Increasing global competition, rapidly changing markets, and greater consumer awareness have altered the way in which corporations do business. To become more efficient, many industries have sought to model some operational aspects by gigantic optimization problems. It is not atypical to encounter models that capture 10 6
Schulz, Andreas S.   +2 more
openaire   +4 more sources

New Equivalent Model of a Quantizer With Noisy Input and Its Applications for MIMO System Analysis and Design

open access: yesIEEE Access, 2020
We propose a novel equivalent model for a quantizer with noisy input (the desired signal corrupted by measurement noise). It presents the quantizer output as a sum of the desired signal after it passes through a nonlinear element with a known equivalent ...
Arkady Molev-Shteiman   +4 more
doaj   +1 more source

On minimal blocking sets of the generalized quadrangle $Q(4, q)$ [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2005
The generalized quadrangle $Q(4,q)$ arising from the parabolic quadric in $PG(4,q)$ always has an ovoid. It is not known whether a minimal blocking set of size smaller than $q^2 + q$ (which is not an ovoid) exists in $Q(4,q)$, $q$ odd. We present results
Miroslava Cimráková, Veerle Fack
doaj   +1 more source

An algorithm for the T-countAn algorithm for the T-count

open access: yesQuantum Information and Computation, 2014
We consider quantum circuits composed of Clifford and $T$ gates. In this context the $T$ gate has a special status since it confers universal computation when added to the (classically simulable) Clifford gates. However it can be very expensive to implement fault-tolerantly.
Michele Mosca   +3 more
openaire   +3 more sources

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

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