Results 81 to 90 of about 9,995,501 (376)

The Elements of Flexibility for Task-Performing Systems

open access: yesIEEE Access, 2023
What makes living systems flexible so that they can react quickly and adapt easily to changing environments? This question has not only engaged biologists for decades but is also of great interest to computer scientists and engineers who seek inspiration
Sebastian Mayer   +2 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Design and Simulation of a Hierarchical Parallel Distributed Processing Model for Orientation Selection Based on Primary Visual Cortex

open access: yesBiomimetics, 2023
The study of the human visual system not only helps to understand the mechanism of the visual system but also helps to develop visual aid systems to help the visually impaired.
Hui Wei, Jingyong Ye, Jiaqi Li, Yun Wang
doaj   +1 more source

Algorithms for Coloring Quadtrees

open access: yes, 1999
We describe simple linear time algorithms for coloring the squares of balanced and unbalanced quadtrees so that no two adjacent squares are given the same color.
Bern, Marshall W.   +2 more
core   +2 more sources

Algorithmics of Diffraction [PDF]

open access: yesActa Physica Polonica B Proceedings Supplement, 2019
Diffraction and Low-x 2018 proceedings (Acta Phys. Pol.
openaire   +4 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

On minimal blocking sets of the generalized quadrangle $Q(4, q)$ [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2005
The generalized quadrangle $Q(4,q)$ arising from the parabolic quadric in $PG(4,q)$ always has an ovoid. It is not known whether a minimal blocking set of size smaller than $q^2 + q$ (which is not an ovoid) exists in $Q(4,q)$, $q$ odd. We present results
Miroslava Cimráková, Veerle Fack
doaj   +1 more source

Evolutionary Algorithms [PDF]

open access: yes, 2018
Evolutionary algorithms (EAs) are population-based metaheuristics, originally inspired by aspects of natural evolution. Modern varieties incorporate a broad mixture of search mechanisms, and tend to blend inspiration from nature with pragmatic engineering concerns; however, all EAs essentially operate by maintaining a population of potential solutions ...
Michael A. Lones, David Corne
openaire   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Packing Three-Vertex Paths in a Subcubic Graph [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2005
In our paper we consider the $P_3$-packing problem in subcubic graphs of different connectivity, improving earlier results of Kelmans and Mubayi. We show that there exists a $P_3$-packing of at least $\lceil 3n/4\rceil$ vertices in any connected subcubic
Adrian Kosowski   +2 more
doaj   +1 more source

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