Results 81 to 90 of about 5,408,588 (346)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Packing Three-Vertex Paths in a Subcubic Graph [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2005
In our paper we consider the $P_3$-packing problem in subcubic graphs of different connectivity, improving earlier results of Kelmans and Mubayi. We show that there exists a $P_3$-packing of at least $\lceil 3n/4\rceil$ vertices in any connected subcubic
Adrian Kosowski   +2 more
doaj   +1 more source

Buddy Algorithms [PDF]

open access: yesThe Computer Journal, 1987
Algorithms are derived for allocating and deallocating blocks of memory using binary buddy, weighted buddy and variant weighted buddy partitioning; and transformations are demonstrated for converting recursive into non-recursive forms. Algorithms are given for the relatively difficult computation of the addressed and size of a buddy slot in the ...
Challab, D. J., Roberts, J. D.
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Cache-Oblivious VAT-Algorithms [PDF]

open access: yes, 2014
The VAT-model (virtual address translation model) extends the EM-model (external memory model) and takes the cost of address translation in virtual memories into account. In this model, the cost of a single memory access may be logarithmic in the largest
Jurkiewicz, Tomasz   +2 more
core  

Scheduling Algorithms for Procrastinators

open access: yes, 2006
This paper presents scheduling algorithms for procrastinators, where the speed that a procrastinator executes a job increases as the due date approaches. We give optimal off-line scheduling policies for linearly increasing speed functions.
A. Bachman   +19 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Exponential quantum advantages in learning quantum observables from classical data

open access: yesnpj Quantum Information
Quantum computers are believed to bring computational advantages in simulating quantum many-body systems. However, recent works have shown that classical machine learning algorithms are able to predict numerous properties of quantum systems with ...
Riccardo Molteni   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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