Results 101 to 110 of about 272,600 (304)

Enhancing collaboration between ecologists and computer scientists: lessons learned and recommendations forward

Ecosphere, 2019
In the era of big data, ecologists are increasingly relying on computational approaches and tools to answer existing questions and pose new research questions.
Cayelan C. Carey, Nicole K. Ward, Kaitlin J. Farrell, Mary E. Lofton, Arianna I. Krinos, Ryan P. McClure, Kensworth C. Subratie, Renato J. Figueiredo, Jonathan P. Doubek, Paul C. Hanson, Philip Papadopoulos, Peter Arzberger   +11 more
doaj   +1 more source

Artificial Intelligence Algorithms Inspired By Life Sciences

Journal of the Turkish Chemical Society, Section A: Chemistry, 2018
Nature and life include many mysterious events, behaviors and format within themselves. There is harmony between the environmental conditions, behavior and forms of all living organism.
Hüseyin Turgut
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Linear time algorithms for finding and representing all the tandem repeats in a string

, 2004
Gusfield D, Stoye J. Linear time algorithms for finding and representing all the tandem repeats in a string. Journal of computer and system sciences. 2004;69(4):525-546.A tandem repeat (or square) is a string [alpha][alpha], where [alpha] is a non-empty ...
Stoye, Jens, Stoye, Jens ; https://orcid.org/, Gusfield, Dan   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

On the discrete adjoints of adaptive time stepping algorithms

, 2008
We investigate the behavior of adaptive time stepping numerical algorithms under the reverse mode of automatic differentiation (AD). By differentiating the time step controller and the error estimator of the original algorithm, reverse mode AD generates ...
Alexe, Mihai, Sandu, Adrian
core  

Algorithms for CTL System Modification

, 2005
The original publication can be found at www.springerlink.comModel updating, as a new concept to be employed as a standard and universal method for system modification, has been started in [4] and further developed in this paper.
Yan Zhang, Ding, Yulin (Rena), Zhang, Yan, Yulin Ding   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Experimental implementations of stereo matching algorithms in Halide

, 2016
Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2016.Cataloged from PDF version of thesis.Includes bibliographical references (pages 51-52).Currently, most stereo matching algorithms ...
Zhang, Min, M. Eng. Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (2016)
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source