Results 81 to 90 of about 132,096,113 (307)

Department of Computer Science newsletter 2020

, 2020
A Newsletter for Friends and Supporters of the Mines Computer Science ...

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Novel Algorithms for Deductive Games [PDF]

, 2011
[[abstract]]This paper presents two novel algorithms for deductive games. First, a k-way-branching algorithm, taking advantage of a clustering technique, is able to efficiently obtain an optimal strategy in the worst case and a near-optimal strategy in ...
Chen, Shan-Tai;Lin, Shun-Shii
core  

How The Social Construction of Disciplinary Boundaries and Disciplinary Hierarchies Shapes What Computer Science Gets Done

Philosophia Scientiæ
What are the core topics of Computer Science, and how are these topics studied? Those are the central questions of the Philosophy of Computer Science. However, how those questions are to be answered is a matter of ongoing debate and social construction ...
Felienne Hermans
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Computer Science Concepts - Data structures and algorithms

, 2010
This lecture forms part of the "Data structures and algorithms" topic of the Computer Science Concepts module.
Rong Yang, UKOER, Open Educational Repository in Support of Computer Science   +2 more
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A generalized approach to construct benchmark problems for dynamic optimization [PDF]

, 2008
Copyright @ Springer-Verlag Berlin Heidelberg 2008.There has been a growing interest in studying evolutionary algorithms in dynamic environments in recent years due to its importance in real applications.
Yang, S, Li, Changhe, Shengxiang Yang, Yang, Shengxiang, Changhe Li, Li, C   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

From nature to computation: Bio-inspired optimization techniques and applications [PDF]

EPJ Web of Conferences
In recent years, various fields, including biology, mathematics, and computer science, have begun to use bio-inspired optimization techniques. When dealing with optimization issues, these methods emerge.
Goswami Chandrashekhar, Shieh Chin-Shiuh, Chakrabarti Prasun   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source