Results 91 to 100 of about 272,600 (304)

Alk: A Formal-Methods-based Educational Platform for Enhancing Algorithmic Thinking

open access: yesScientific Annals of Computer Science
Algorithm design courses are fundamental to computer science curricula, but fostering algorithmic thinking in students is challenging due to the diverse skills and creativity required. Dedicated teaching support tools can help both course instructors and
Alexandru-Ioan Lungu   +4 more
doaj   +1 more source

The Importance of Computer Science in K12 Curriculum

open access: yes, 2020
8 p.Critical thinking and complex problem solving are two of the most important skills employers are looking for, and a strong foundation in both allows students to excel in the workforce.
Tibbetts, Dustin
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Dynamic Programming in Computer Science

open access: yes, 1979
This paper is a survey of dynamic programming algorithms for problems in computer science. For each of the problems the author derives the functional equations and provides numerous references to related results.
K. Brown
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

International ICST Conference on Theory and Practice of Algorithms in (Computer) Systems, TAPAS

open access: yes, 2011
In the light of continuously increasing interaction between communication and computing, there arise a number of interesting, and difficult algorithmic issues in diverse areas including coverage, mobility, routing, cooperation, capacity planning ...
M. Segal, MARCHETTI SPACCAMELA, Alberto
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Selected Remarks about Computer Processing in Terms of Flow Control and Statistical Mechanics

open access: yesEntropy, 2016
Despite the fact that much has been said about processing in computer science, it seems that there is still much to do. A classical approach assumes that the computations done by computers are a kind of mathematical operation (calculations of functions ...
Dominik Strzałka
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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