Results 71 to 80 of about 272,600 (304)

Algorithmic Thinking Skills without Computers for Prospective Computer Science Teachers

Kuramsal Eğitimbilim, 2021
Algoritmik düşünme becerileri bu yüzyılda yaşayan herkes için gerekli bir özellik olarak düşünülebilir. Günümüzde bireyler ve toplumlar bilgi iletişim teknolojilerini (BİT) kullanmak durumunda kalıyorlar. Bu durum onların BİT okuryazarı olmalarını gerektirmektedir. Bu gerekliliğin karşılanmasında öğretmenlere önemli görev düştüğü söylenebilir.
openaire   +5 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Generic Tasks for Algorithms

Future Internet, 2020
Due to its links to computer science (CS), teaching computational thinking (CT) often involves the handling of algorithms in activities, such as their implementation or analysis. Although there already exists a wide variety of different tasks for various
Gregor Milicic, Sina Wetzel, Matthias Ludwig   +2 more
doaj   +1 more source

Using algorithm visualizations in computer science education

Open Computer Science, 2014
Abstract Algorithm visualization illustrates how algorithms work in a graphical way. It mainly aims to simplify and deepen the understanding of algorithms operation. Within the paper we discuss the possibility of enriching the standard methods of teaching algorithms, with the algorithm visualizations.
openaire   +2 more sources

A high‐impact and expeditious journal for computational and algorithmic computer science research

Computer-Aided Civil and Infrastructure Engineering, 2021
Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public ...
openaire   +2 more sources

ALGORITHM IS A FUNDAMENTAL CONCEPT IN COMPUTER SCIENCE

, 2023
An algorithm is a clear sequence of actions aimed at achieving a goal or solving a problem. The history of the development of algorithms has come a long way from intuitive understanding and spontaneous application to awareness of patterns and practical use in modern computers and computer systems.
openaire   +2 more sources

Computer Science Concepts - Data structures and algorithms

, 2010
This lecture forms part of the "Data structures and algorithms" topic of the Computer Science Concepts module.
Rong Yang, UKOER, Open Educational Repository in Support of Computer Science   +2 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

How The Social Construction of Disciplinary Boundaries and Disciplinary Hierarchies Shapes What Computer Science Gets Done

Philosophia Scientiæ
What are the core topics of Computer Science, and how are these topics studied? Those are the central questions of the Philosophy of Computer Science. However, how those questions are to be answered is a matter of ongoing debate and social construction ...
Felienne Hermans
doaj   +1 more source