Results 111 to 120 of about 87,499 (307)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Elevages de glossines. Synthèse [PDF]
, 1984 Après un bref historique, les auteurs décrivent les différentes modalités qui ont été mises au point, au cours des 20 dernières années, pour obtenir des élevages autonomes de glossines atteignant parfois des effectifs considérables, grâce auxquels des ...
Bauer, Burkhard, Itard, Jacques
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
VALUATION OF TARGET FIRMS ACQUIRED IN THE FOOD SECTOR DURING THE 1996-2001 WAVE [PDF]
The paper studies valuation ratios of food companies that were part of mergers & acquisitions (M&A) involving at least one French company during the 1996-2001 period. Results converge to value the food company 1.1 to 1.4 times its turnover.
Declerck, Francis
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Calenda, 2004 Terrains & travaux, la revue de sciences sociales de l’Ecole Normale Supérieure de Cachan, consacre un numéro spécial à l’alimentation, à paraître en octobre 2005.
openaire +3 more sources
CONSIDERATIONS ABOUT PUBLIC HOUSING POLICY [PDF]
The field of house construction in Romania is confrunting in the transition period through a real democratic system with remarkable aspects. It’s about, first of all, the human rights: that the owner of a home, which correspond to the requirements of ...
Cristian Silviu BANACU +2 more
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Management of intestinal transplantation in humans [PDF]
, 1992 We report here the clinical experience and management guidelines for the nine consecutive cases who received either an isolated small intestinal graft (n = 1) or an intestine liver combination at the University of Pittsburgh, with FK 506 being the basic ...
Abu-Elmagd, K +14 more
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