Results 101 to 110 of about 87,499 (307)
Common Language Created by Legislation Regarding the Teritorial Limit of the Production Vine Wine Potential of Romania [PDF]
Trying to build a future according to the one of EU and aspiring after becoming an apreciate member of the International Wine Community, as a producer of some valuable wines, Romania has intensified the efforts to reach these issues, to create a common ...
Ionica Soare
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The effect of different levels of spring grass supply and stocking rate on the performance and intake of cows in early lactation [PDF]
, 2008 End of project reportGrazed herbage can supply nutrients to dairy cows at a lower cost than alternative feeds (Shalloo et al., 2004). Therefore, the objective of pasture-based systems must be to maximize the proportion of grazed grass in the diet of the ...
Delaby, Luc +4 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
L'alimentation à Tours à la fin du Moyen Age [PDF]
, 2011 Panneaux d'une exposition aux Archives municipales de Tours (France) du 18 novembre 2011 au 6 janvier 2012Du 18 novembre 2011 au 6 janvier 2012 s'est tenue aux archives municipales de Tours une exposition sur l'Alimentation à Tours à la fin du Moyen Age.
Boisseuil, Didier, Leturcq, Samuel
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