Results 41 to 50 of about 84,539 (289)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Intensive Care Units (ICUs), and Ordinary Means: Turning Virtue Into Vice [PDF]
, 1990 There is a social process by which what have been virtues in one social context can become vices in another. Alasdair MacIntyre 1
Bole III, Thomas J.
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Revista Latino-Americana de Enfermagem, 2000 O objetivo deste estudo é descrever a criança portadora de deformação congênita lábio palatal, enfatizando sua alimentação, as dificuldades e os métodos alternativos para alimentar a criança, e assistência de enfermagem neste processo.
Raimunda da Costa Araruna +1 more
doaj +1 more source
Heritage entrepreneurship. Agency-driven promotion of the Mediterranean diet in Spain. [PDF]
, 2015 This article explores the role of the agency in the social process that constitutes cultural heritage. By introducing the concept of heritage entrepreneurship to explain the conversion of cultural elements into heritage, we discuss the case of the ...
Pfeilstetter, Richard
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Utopías y sueños: El deseo de comer mucho y comer bien
E-Spania, 2015 Le mythe d’une terre d’abondance naît d’une société injuste et opprimée qui n’offre, comme seul baume, que le rêve en un monde meilleur. La nourriture, nécessité première des êtres humains quels que fussent l’époque et le lieu, devint la principale ...
María Ángeles Pérez Samper
doaj +1 more source
Les personnes exilées et les associations locales en temps de pandémie : d’une crise à l’autre
Lien Social et Politiques, 2022 Les actions associatives développées avec les personnes exilées s’inscrivent dans des crises durables de l’accueil et de la solidarité. Le confinement de la population instauré en mars 2020 a eu des effets sur le rôle des acteurs associatifs. Dans quelle
Fransez Poisson +2 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source