Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source
Base-Catalyzed Alcoholysis of <i>N</i>‑Acylpyrrole-Type Amides Under Mild Conditions. [PDF]
Yang PF +5 more
europepmc +1 more source
Multi‐Contrast Human Brain CEST MRI at 11.7 T: First In Vivo Demonstration
ABSTRACT PurposeTo implement and evaluate chemical exchange saturation transfer (CEST) at ultra‐high field on a whole‐body 11.7 T scanner using parallel transmission (pTx). MethodsTailored pTx CEST saturation pulses were optimized to achieve a spatially uniform target B1+ while satisfying SAR and power constraints either defined by conservatively ...
Camélia Ressam +11 more
wiley +1 more source
Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides. [PDF]
Moriyama Y, Sada H, Nanjo T.
europepmc +1 more source
Elevation‐dependent soil and plant responses to a decade of warming and species removal
Understanding how ecosystems retain or release carbon under warming is a critical challenge. Dominant plant species, which contribute the most biomass, can mediate ecosystem responses to warming by modifying microclimate and nutrient cycling. To investigate how warming and shifts in plant dominance interact to affect carbon and nutrient dynamics, we ...
Anna Wootton +6 more
wiley +1 more source
Soybean oil fatty acid aromatic amides as dual-functional inhibitors and antimicrobial agents: synthesis, characterization, thermal stability, and performance evaluation. [PDF]
Dadashova NK +11 more
europepmc +1 more source
Schematic diagram of RAFT polymerization of acrylate monomers. ABSTRACT This study reports the synthesis of a macro‐RAFT agent based on poly(ɛ‐caprolactone) (PCL) via ring‐opening polymerization (ROP), which was subsequently used to prepare acrylate‐based block and block‐graft copolymers through RAFT polymerization.
Melahat Göktaş, Cengiz Aykaç
wiley +1 more source
Unsaturated biobased polyesters from bicyclic α‐pinene‐based diols
We present the synthesis of four biosourced unsaturated polyesters made from chiral terpene‐based diols and esters of renewable diacids. The resulting materials harbor a bicyclic pinene ring in their backbones which leads to enhanced thermal properties while still conferring susceptibility to enzyme hydrolysis for chains having a cis alkene.
Ganapathy Ranjani +4 more
wiley +1 more source
Recent progress on Ni-catalysed alkyl-alkyl cross-coupling enabled by asymmetric hydrofunctionalization of alkenes. [PDF]
He J, Kumar PB, Li Y, Yu Q, Shu W.
europepmc +1 more source
ABSTRACT N‐vinylamides, especially noncyclic N‐vinylacetamide (NVA), have been used in various applications such as biomaterials, surfactants, and hydrogels. However, their potential to copolymerize with cyclic ketene acetal (CKA) to create degradable polymers is underexplored.
Mukmin Sapto Pamungkas +2 more
wiley +1 more source

