Results 191 to 200 of about 33,029 (246)

Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases. [PDF]

Angew Chem Int Ed Engl
Damian M, Tseliou V, Peters P, Knaus T, Mutti FG.   +4 more
europepmc   +1 more source

Triple‐Negative Breast Cancer Versus Non‐Triple‐Negative Breast Cancer: The Impact of Pd and Pt Complexes on Basal‐Like Triple‐Negative Breast Cancer

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
The anticancer activity of the complexes Pd3Spd2, Pt3Spd2, Pt2Put2(NH3)4 and Pd2Put2 against human TNBC, non‐TNBC and healthy breast cells was evaluated. The metabolic impact of the most promising metal complexes—Pd3Spd2 and Pt2Put2(NH3)4—was further assessed using vibrational microspectroscopies, providing detailed insights into the drug‐induced ...
Clara B. Martins, Maria P. M. Marques, Luís A. E. Batista de Carvalho, Ana L. M. Batista de Carvalho   +3 more
wiley   +1 more source

Se-catalyzed enantioselective lactamization enabled by a <i>N</i>-fluorosulfonyl group: total synthesis of diaporisoindole A. [PDF]

Chem Sci
Yamamoto D, Yamasaki S, Hashimoto T.
europepmc   +1 more source

Inhibitors Targeting SARS‐CoV‐2 Papain‐Like Protease: Screening, Design, Synthesis, and Biological Evaluation

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
In our study, we obtained both non‐covalent and covalent PLpro inhibitors. Additionally, the stable protein‐ligand interactions of the active compound were examined using advanced computational docking and molecular dynamics simulations. The non‐covalent inhibitor 2t showed antiviral activity with an EC50 of 2.89 µM, indicating its potential as a ...
Elena‐Oriana Iuga, Nilu Gone, Mariana Ortiz de Godoy, Gabriel Correa Verissimo, Giovanna de Jesus Agostinetto, Liam Urich, Nadine Krüger, Thales Kronenberger, Rafael Victorio Carvalho Guido, Anthony J. O’Donoghue, Stefan A. Laufer, Thanigaimalai Pillaiyar   +11 more
wiley   +1 more source

Synthesis of Amides from Amines and Esters Under Hydrothermal Conditions. [PDF]

ChemistryOpen
Brown PA, Aspin A, Yang Z.
europepmc   +1 more source

Mechanochemical Near‐Ambient Synthesis of C2N Materials From HAT‐CN and its Precursors

ChemSusChem, Volume 19, Issue 9, 14 May 2026.
The synthesis of C2N‐type materials was dominated by temperature‐based materials. Herein, we present two innovative mechanochemical pathways to synthesize those materials, revealing the significant impact of energy input per single‐impact on the structure and yield.
Pascal Dippner, Sven Grätz, Jonas Lins, Torsten Gutmann, Lars Borchardt   +4 more
wiley   +1 more source

Aldehydes as CO Releasing Molecules: <i>In Situ</i> and <i>Ex Situ</i> Giese Reactions and Palladium-Catalyzed Aminocarbonylations. [PDF]

Org Lett
Cassera E, Fagnoni M.
europepmc   +1 more source

Flow Chemistry Meets Green Solvents: Telescoped Synthesis of Triazolyl Phosphoramidates and Phosphinamides in γ‐Valerolactone

ChemSusChem, Volume 19, Issue 9, 14 May 2026.
A telescoped three‐step continuous flow process enables the synthesis of organophosphorus 1,2,3‐triazoles in the biomass‐derived solvent γ‐valerolactone (GVL). The sequence integrates N‐phosphorylation, azidation, and Cu(I)‐catalyzed azide–alkyne cycloaddition (CuAAC), followed by in‐line copper removal, giving diverse triazoles in good to high overall
Viktória Gerő, Dániel Steinsits, Pál Tamás Szabó, Erika Bálint   +3 more
wiley   +1 more source

Synthesis of Spiro Carbocycles via Methyl β-C(sp³)-H Functionalization of Cyclic Aliphatic Acids. [PDF]

J Am Chem Soc
Sheng T, Zhao Z, Lu Y, Chekshin N, Yu JQ.   +4 more
europepmc   +1 more source

Highly Versatile Hydrogenative Functionalizations of Phthalimides Catalyzed by an Ag‐Alumina Zeolite Nanocomposite: One‐Pot Synthesis of 3‐Substituted Isoindolinones

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
Heterogeneous‐catalyzed selective and versatile hydrogenative functionalizations of phthalimides have been developed for the first time. By using a solid nanocomposite formed by [Ag/Al2O3] material in combination with [H‐BETA] zeolite as cocatalyst, a broad range of 3‐functionalized isoindolinones have been accesed in one‐pot from phthalimides, H2 and ...
Carles Lluna‐Galán, Rosa Adam, Jose R. Cabrero‐Antonino   +2 more
wiley   +1 more source