Frontiers in manganese catalysis: a sustainable platform for bond construction and heterocycle synthesis. [PDF]
Das AK +7 more
europepmc +1 more source
Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova +6 more
wiley +1 more source
Stereoselective Bio-Organocatalytic Cascade to Chiral Amides as Active Pharmaceutical Ingredient Intermediates Using ω-Transaminase and Choline Chloride Under Microwave Irradiation. [PDF]
Romano S +7 more
europepmc +1 more source
Misfolding mutations in pancreatic lipase have been identified as potential contributors of chronic pancreatitis, an inflammatory disease of the human pancreas. Here, we describe the effect of these misfolding mutations on pancreatic lipase structure using molecular dynamics simulations and structural modeling.
Gyula Hoffka, András Szabó
wiley +1 more source
Photoinduced Cleavage of Alkenyl Fluorides for Nucleophilic Acyl Substitution via In Situ Generated Acyl Fluorides. [PDF]
Gogarnoiu ES +5 more
europepmc +1 more source
Benign by design: A paradigm shift in cosmetic ingredient development
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota +3 more
wiley +1 more source
Fair and Square: Design, Synthesis and Biological Evaluations of Squaric Acid Derivatives as Novel HDAC8 Inhibitors. [PDF]
Long N +3 more
europepmc +1 more source
Abstract A substantial fraction of organic carbon in carbonaceous chondrites has long been described as “missing,” reflecting incomplete recovery and limited resolution of operationally defined organic components. Here, we present a quantitative reassessment of the carbon budget in the Murchison meteorite using an integrated extraction–recovery mass ...
Hina Dohi +2 more
wiley +1 more source
Additive-Controlled Divergent Synthesis of Amides and Ketones via Ni/Photoredox-Catalyzed Deoxygenative Functionalization of Alcohols. [PDF]
Xu P, Ma C.
europepmc +1 more source
Mineralogy, mineral chemistry, and redox equilibria in ten aggregate particles from asteroid Bennu
Abstract Examination of 10 Bennu aggregate particles has revealed the presence of many phases which taken together can provide constraints on the oxygen fugacity (fO2) of Bennu samples. Phyllosilicates (saponite and serpentine), carbonates, oxides (magnetite, chromite), sulfides (pyrrhotite, pentlandite), phosphate (hydroxyapatite, Na‐Mg‐phosphate ...
K. Righter +11 more
wiley +1 more source

