Results 21 to 30 of about 5,245 (170)
Space‐based remote imaging spectroscopy of the Aliso Canyon CH4 superemitter [PDF]
Geophysical Research Letters, 2016 AbstractThe Aliso Canyon gas storage facility near Porter Ranch, California, produced a large accidental CH4 release from October 2015 to February 2016. The Hyperion imaging spectrometer on board the EO‐1 satellite successfully detected this event, achieving the first orbital attribution of CH4 to a single anthropogenic superemitter.
D. R. Thompson +9 more
openaire +4 more sources
The FEBS Journal, EarlyView.Some prenylated flavin mononucleotide (prFMN) synthases exceptionally prefer dimethylallyl phosphate (DMAP) over dimethylallyl diphosphate (DMAPP), which is a common prenyl donor substrate for many prenyltransferases. Structural and mutagenic analyses of Methanosarcina mazei prFMN synthase, which prefers DMAP but can also accept DMAPP, elucidated its ...
Sou Fukuhara +5 more
wiley +1 more source
Protein Science, Volume 35, Issue 9, September 2026.Abstract Under selective drug pressure, the structure and dynamics of HIV‐1 protease (PR) evolve to confer resistance to the drug. Here, we report on the conformational changes in PR flaps for drug‐resistance mutations using 19F nuclear magnetic resonance (NMR) spectroscopy.
Michel Guerrero +9 more
wiley +1 more source
Cancer Medicine, 2022 Purpose Multigene panels allow simultaneous testing of genes involved in cancer predisposition. Thyroid cancer (TCa) is a component tumor of several cancer predisposition syndromes, but the complete landscape of germline variants predisposing to TCa ...
Junne Kamihara +6 more
doaj +1 more source
Prevalence of Phelan McDermid Syndrome Estimated To Be ~1:7300 Using a Multisource Model
Autism Research, Volume 19, Issue 8, August 2026.ABSTRACT Estimating the prevalence of genetic disorders is complicated by many factors including sampling bias and differing methods of estimation. However, establishing the true prevalence of these disorders is critical for understanding disease burden, pharmacoeconomic modeling, and resource allocation for testing and care.
Tess Levy +22 more
wiley +1 more source
Revista de Investigación en Agroproducción Sustentable, 2017 El estudio se realizó en el distrito de Molinopampa en el departamento de Amazonas, cuyo objetivo fue seleccionar Árboles Plus de las especies maderables de “aliso” Alnus acuminata, “cedro” Cedrela odorata e “ishpingo” Ocotea sp.
Mario Oliva, Ysaías Rimachi
doaj +1 more source
Brain and Behavior, Volume 16, Issue 8, August 2026.ABSTRACT Background To compare the outcomes of bridging therapy versus intravenous thrombolysis (IVT) alone in patients with medium vessel occlusion (MeVO). Methods Consecutive MeVO patients between January 2019 and December 2024 were retrospectively included and classified into IVT alone or bridging therapy groups.
Di Hu +6 more
wiley +1 more source
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
The FEBS Journal, Volume 293, Issue 15, Page 4533-4553, August 2026.Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
Stem Cells International, 2012 Culturing stem cells for an extended period of time can lead to acquired chromosomal aberrations. Determining the copy number variant (CNV) profile of stem cell lines is critical since CNVs can have dramatic effects on gene expression and tumorigenic ...
Aaron M. Elliott +2 more
doaj +1 more source