Results 41 to 50 of about 21,558 (210)

The Hidden Influence: Impacts of Residual Dimethylformamide in NDSB‐211 on icIEF Separation for Monoclonal Antibodies

ELECTROPHORESIS, Volume 46, Issue 19, Page 1502-1512, October 2025.
ABSTRACT Monoclonal antibodies (mAbs) present analytical challenges due to their inherent heterogeneity and susceptibility to post‐translational modifications (PTMs) during production and storage. Monitoring of charge heterogeneity profiles by imaged capillary isoelectric focusing (icIEF) has been aided by the use of non‐detergent sulfobetaines (NDSBs),
Delaney Doran, Matthew Myers, Katarina Moravcevic, Steven LaBrenz, Pinger Wang, Xiaoying Ji   +5 more
wiley   +1 more source

Evolution of Allorecognition in the Tunicata

Biology, 2020
Allorecognition, the ability to distinguish self or kin from unrelated conspecifics, plays several important biological roles in invertebrate animals. Two of these roles include negotiating limited benthic space for colonial invertebrates, and inbreeding
Marie L. Nydam
doaj   +1 more source

Biochemical and Biophysical Properties of Extracellular Matrix Nanofibers Modulate iPSC‐Derived Human Hepatocyte Maturation

Journal of Biomedical Materials Research Part A, Volume 113, Issue 10, October 2025.
ABSTRACT Human liver models grown in the lab are used for testing drug metabolism and toxicity, studying liver diseases, and developing new therapies. Induced pluripotent stem cell (iPSC)‐derived hepatocyte‐like cells (HLCs) provide a renewable alternative to scarce primary human hepatocytes (PHHs), but they remain functionally immature compared to ...
Yang Yuan, Liszt C. Madruga, Kristen Y. Cotton, Matt J. Kipper, Salman R. Khetani   +4 more
wiley   +1 more source

Taxonomy and dated molecular phylogeny of Allium oreophilum sensu lato (A. subg. Porphyroprason) uncover a surprising number of cryptic taxa

TAXON, Volume 74, Issue 5, Page 1035-1053, October 2025.
Abstract Allium oreophilum, hitherto the representative of the monotypic A. subg. Porphyroprason from the second evolutionary lineage of Allium, is studied in detail. Over about 150 years, A. oreophilum was regarded as a somewhat polymorphous species with two synonyms, all described in the 19th century.
Nikolai Friesen, Georgy Lazkov, Igor G. Levichev, Mathias Leweke, Daulet Abdildanov, Nazgul Turdumatova, Ramazan Murtazaliev, Smatula Dzumanov, Gulnara T. Sitpayeva, Polina Vesselova, Vladimir Epiktetov, Kuddisi Ertuğrul, Osman Tugay, Reinhard M. Fritsch   +13 more
wiley   +1 more source

Número de cromosomas de Alnus acuminata H.B. K. Chromosomes number of specie Alnus acuminata H.B.K.

Agronomía Colombiana, 1989
El árbol de Aliso, Alnus scuminsta H.B.K. es una de -las especies más recomendadas en reforestación y por su economía<br />es motivo de estudio. Se comprobó que su número cromosómico es de 2n= 28.The Aliso tree, Alnus acuminata H.B.K., is one of ...
Coba de Gutierrez Bertha, Alvarado de Coral Cecilia   +1 more
doaj  

Implementing a Genetic Counselor‐Led Model for Hereditary Myeloid Malignancies: A Real‐World Study

Cancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Background Hereditary hematological malignancy syndromes (HHMS) are more common than previously thought, and identification of an HHMS syndrome can inform the choice of treatments, transplant, and testing of other family members. Genetic testing guidelines for hematological malignancy have broadened; however, there remain a multitude of ...
Madeline VanDerGraaf, Georgianne Younger, Kyle Dillahunt, Jennifer Smith, Athena Puski, Nicole Blum, Hailey Manwiller, Jaime Nagy, Grerk Sutamtewagul, Kittika Poonsombudlert, Moon Ley Tung   +10 more
wiley   +1 more source

Macroinvertebrados acuáticos de la quebrada Los Alisos, Firavitoba - Boyacá

Intropica, 2016
Se presenta la composición y algunas implicaciones funcionales de los macroinvertebrados acuáticos existentes en la cabecera de la quebrada Los Alisos, ubicada al occidente del municipio de Firavitoba en el departamento de Boyacá. Se realizaron dos muestreos durante los meses de agosto y septiembre de 2016.
Néstor Ned Torres-Zambrano, David Rolando Torres-Zambrano   +1 more
openaire   +2 more sources

Clinically Important Endpoints in Individuals With Leukodystrophy: A Multisite Study

Annals of the Child Neurology Society, Volume 3, Issue 3, Page 176-187, September 2025.
ABSTRACT Importance Leukodystrophies are a diverse group of rare disorders that disrupt central myelination. These disorders present with a broad spectrum of neurological severity and are associated with a range of potential secondary complications, such as scoliosis and failure of independent feeding.
Emma R. Kotes, Sarah Woidill, Russell D'Aiello, Amina Khan, Jacob McCann, Mark Ramos, Francesco Gavazzi, Stephanie Keller, Keith Van Haren, Ali Fatemi, Florian Eichler, Joshua Bonkowsky, Jamie Fraser, Lisa Emrick, Omar Sherbini, Ashley Hackett, Jeilo Gauna, Dandre Amos, Jordan Goodman, Amena Smith Fine, Amanda Nagy, Seungil Lee, Nicole Page, Johanna Schmidt, Amy Pizzino, Kayla Muirhead, Mariko Bennett, Amy Waldman, Justine Shults, Laura Adang, Robert Grundmeier, Adeline Vanderver   +31 more
wiley   +1 more source

Re‐engineering a transferase scaffold for indole C3 methylation in diketopiperazines

Protein Science, Volume 34, Issue 9, September 2025.
Abstract The pyrroloindole (hexahydropyrrolo[2,3‐b]indole, HPI) structural motif is present in a wide range of natural products with various biological activities, yet its chemical synthesis poses a challenge, particularly regarding methylation at the indole C3 position.
Mona Haase, Oliver H. Weiergräber, Jörg Pietruszka   +2 more
wiley   +1 more source

Detection of Methane Emission from a Local Source Using GOSAT Target Observations

Remote Sensing, 2020
Emissions of atmospheric methane (CH4), which greatly contributes to radiative forcing, have larger uncertainties than those for carbon dioxide (CO2). The Thermal And Near-infrared Sensor for carbon Observation Fourier-Transform Spectrometer (TANSO-FTS ...
Akihiko Kuze, Nobuhiro Kikuchi, Fumie Kataoka, Hiroshi Suto, Kei Shiomi, Yutaka Kondo   +5 more
doaj   +1 more source