Results 61 to 70 of about 278,714 (311)

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou   +23 more
wiley   +1 more source

The Application of Alizarin Red S in the Fluid-inclusion Homogenization Temperature Measurement of Carbonate Rocks from the Middle Permian Qixia Formation, Western Sichuan Basin

open access: yesYankuang ceshi, 2015
The accurate identification of host mineral and the formation stage of fluid inclusions are critical to temperature measurement, and the combination of inclusion technology and other technologies could be better to figure out the source and properties ...
LAN Ye-fang   +4 more
doaj   +1 more source

Green synthesis, characterization, antimicrobial studies of NiO nanoparticles and enhanced photocatalytic degradation of organic pollutant

open access: yesRomanian Journal of Ecology & Environmental Chemistry, 2023
Nanoparticles differ significantly from their bulk counterparts in terms of their characteristics, and they have a wide range of scientific uses. The use of green nanoparticles have received considerable attention.
Kalyanasundaram Indhu   +2 more
doaj   +1 more source

The expression of ALP and alizarin red-S staining.

open access: yes, 2014
(A) Images of ALP staining of rat P-MSCs with or without NPWT treatment of different daily duration for 7 days.
Zonghuan Li (391740)   +4 more
core   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Effects of Connective Tissue Growth Factor on the Cell Viability, Proliferation, Osteogenic Capacity and mRNA Expression of Stem Cell Spheroids

open access: yesApplied Sciences, 2021
Background: Connective tissue growth factor (CTGF) is a cellular communication network factor family protein involved in many cellular functions. The purpose of this study was to determine the effects of CTGF on the proliferation, osteogenic capacity ...
Abdullah Zaki Alnahash   +7 more
doaj   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

open access: yesAdvanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan   +24 more
wiley   +1 more source

Glassy Carbon Electrode Modified with Alizarin Red S as a Working Electrode for the Analysis of Cobalt in Water and Hair Using Adsorptive Stripping Voltammetry

open access: yesInternational Journal of Electrochemical Science, 2019
In the present work, glassy carbon electrode (GCE) modified with Alizarin Red S (ARS) was employed for the determination of cobalt in waters and human hair by square wave cathodic adsorptive stripping voltammetry (SW-CASV).
Hamed M. Al-Saidi   +2 more
doaj   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

open access: yesAdvanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu   +11 more
wiley   +1 more source

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