Results 191 to 200 of about 367,343 (310)

Phosphorylated Chemiluminescent Probe Based on Spiro-cyclobutyl-phenoxy-dioxetane for the In Situ Light-Activated Sensing of Alkaline Phosphatase. [PDF]

Anal Chem
Zhao CJ, Gui WZ, Wang TH, Hu XL, Zhang HY, James TD, He XP.   +6 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Prognostic Value of the Pre-treatment Albumin-to-Alkaline Phosphatase Ratio in Patients With Metastatic Colorectal Cancer. [PDF]

Cureus
Arak H, Gumusburun E, Yesil Cinkir H.
europepmc   +1 more source

Population pharmacokinetic/pharmacodynamic modelling to evaluate favipiravir in combination with lopinavir–ritonavir in patients with COVID‐19

British Journal of Clinical Pharmacology, EarlyView.
Aims The repurposed use of favipiravir in COVID‐19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it may have a measurable effect on the virus in humans.
Akosua A. Agyeman, Laura Buggiotti, Li‐An K. Brown, Jose A. Guerra‐Assuncao, Japhette E. Kembou‐Ringert, Wen Y. Mak, Judith Breuer, David M. Lowe, Joseph F. Standing, FLARE Investigators   +9 more
wiley   +1 more source

A study on the correlation between albumin-to-alkaline phosphatase ratio and the severity of pelvic inflammatory disease. [PDF]

Front Med (Lausanne)
Wang L, Yuan H, Bian P, Yuan J, Yu Y.
europepmc   +1 more source

Correction to “Surface Functionalization of Hydroxyapatite Scaffolds with MgAlEu‐LDH Nanosheets for High‐Performance Bone Regeneration”

Advanced Science, EarlyView.
wiley   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Control of alkaline phosphatase activity and pH stability by taurine in liquid boar semen. [PDF]

J Anim Sci Technol
Dissanayake WMN, Gamage MAGNDMA, Heo JM, Yi YJ.   +3 more
europepmc   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Prognostic value of alkaline phosphatase-to-albumin ratio in critically ill patients with atrial fibrillation: A MIMIC-IV retrospective study. [PDF]

Sci Prog
Yuan Z, Zhao L, Geng H, Ji Q, Zuo K, Luo Y, Liang G, He G.   +7 more
europepmc   +1 more source