Results 211 to 220 of about 367,343 (310)

Studying the evolutionary potential of ancestral aryl sulfatases in the alkaline phosphatase family with droplet microfluidics.

Analyst
Eenink BDG, Holstein JM, Heberlein M, Dilkaute C, Jose J, Hollfelder F, van Loo B, Bornberg-Bauer E, Kaminski TS, Lange A.   +9 more
europepmc   +1 more source

Mineral-targeted alkaline phosphatase improves bone graft-mediated alveolar bone defect healing in mice. [PDF]

J Periodontol
Sawangsri K, Phanrungsuwan A, Leblebicioglu B, Millán JL, Foster BL.   +4 more
europepmc   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

N-linked glycosylation plays an essential role in the stability and function of tissue-nonspecific alkaline phosphatase. [PDF]

J Biol Chem
Atanasova D, Kusay AS, Moparthi L, Koch S, Haarhaus M, Narisawa S, Millán JL, Landberg E, Magnusson P.   +8 more
europepmc   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Nondestructive In-Situ Measurement of Alkaline Phosphatase Activity of Human Intestinal Organoids in Hydrogel Domes Using Scanning Electrochemical Microscopy. [PDF]

Anal Chem
Utagawa Y, Ogihara A, Shinoda Y, Li F, Abe H, Shiku H, Ino K.   +6 more
europepmc   +1 more source

Smoldering Systemic Mastocytosis Without Detectable KIT Mutation: A Debilitating Course and Therapeutic Challenge

Cancer Nexus, EarlyView.
Graphical abstract illustrating the clinical course and treatment response. ABSTRACT Systemic mastocytosis (SM) is a clonal hematologic neoplasm driven by activating KIT mutations, particularly D816V. Indolent SM typically follows a stable course, progression to higher‐burden subtypes is uncommon.
Homeniuk Anna, Medina Esenbekova, Micheal Bishara, Layo Akinrinwoye, Leila Metellus, Joane Titus   +5 more
wiley   +1 more source

Neutrophil-lymphocyte ratio, albumin-alkaline phosphatase ratio, and bilirubin predict outcomes in hepatectomy hepatolithiasis patients. [PDF]

World J Gastrointest Surg
Yang J, Yang YX, Du QJ, Gao HW, Bai YN.
europepmc   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang, Dong‐Gyu Heo, Eunjin Hong   +2 more
wiley   +1 more source

Liver fraction of circulating alkaline phosphatase is elevated in chronic kidney disease and associates with mortality in patients treated with haemodialysis. [PDF]

Clin Kidney J
Smout D, Haarhaus M, D'Haese P, Jørgensen HS, Claes K, Bammens B, Van Craenenbroeck AH, Meijers B, Van Hoof V, Cavalier E, Evenepoel P.   +10 more
europepmc   +1 more source