Results 231 to 240 of about 516,488 (356)

Adaptive Antioxidant Nanomedicines Inhibit Ferroptosis in Renal Tubular Epithelial Cells to Alleviate Diabetic Kidney Disease

Advanced Science, EarlyView.
In this study, an adaptive antioxidant nanodrug (AAN) is developed through the self‐polymerization of L‐selenocysteine. The AAN exhibits dual functionalities: antioxidant activity (scavenging reactive oxygen species) and mitochondrial targeting. Moreover, the released selenium (Se) participates in the synthesis of glutathione peroxidase 4 (GPX4), which
Zerun Liu, Ting Huang, Ying Hong, Yuqi Yang, Wensheng Chen, Qingtao Zeng, Qiaohui Chen, Yongqi Yang, Xiaohong Ying, Wan Zeng, Ziyu Wu, Tianjiao Zhao, Xuesi Wan, Jianlin Chen, Kelong Ai, Qiong Huang   +15 more
wiley   +1 more source

PROPERTIES OF TWO REGULATING GENES FOR ALKALINE PHOSPHATASE [PDF]

, 1962
Alan Garen, Harrison Echols
openalex   +1 more source

THE PHOSPHORYLATION OF ALKALINE PHOSPHATASE [PDF]

Proceedings of the National Academy of Sciences, 1963
openaire   +3 more sources

Alkaline Phosphatase-Targeted, Gadolinium-Labeled Nanoparticles for Enhanced Multimodal Imaging of Liver Cancer. [PDF]

ACS Appl Mater Interfaces
Luo M, Bailey MD, Kim H, Lei Y, Meade TJ.   +4 more
europepmc   +1 more source

BMSC‐NFMC Model for Vascular Regulation and Interface Integration in Osteochondral Regeneration

Advanced Science, EarlyView.
A novel strategy for integrated osteochondral tissue regeneration using BMSC‐NFMCs, this study has demonstrated the precise regulation of vascularization and effective interface integration using optimized nanofibrous materials and innovative construction methods.
Qian Zhou, Mengjie Hou, Baoshuai Bai, Yiwu Zhang, Yiwei Shen, Zenghui Jia, Yongqiang Guo, Guangdong Zhou, Xiaoqin Liang   +8 more
wiley   +1 more source

Clinical presentation of adults with persistently low alkaline phosphatase activity: a retrospective multicentre, cross-sectional study in Germany. [PDF]

BMJ Open
Hoff P, Mann A, Steinmüller M, Aliluev A.   +3 more
europepmc   +1 more source

Phenylalanine‐Based DNA‐Encoded Chemical Libraries for the Discovery of Potent and Selective Small Organic Ligands Against Markers of Cancer and Immune Cells

Advanced Science, EarlyView.
FM‐DEL1 and FM‐DEL2 are constructed by installing one or two sets of building blocks on a phenylalanine central scaffold. FM‐DELs are screened against markers of prostate, and renal cell carcinoma, and against an immunological target expressed on the surface of natural killer cells.
Francesca Migliorini, Andrea Ciamarone, Sheila Dakhel Plaza, Tony Georgiev, Marta Mascellani, Emanuela Sabato, Giulio Vistoli, Ilaria Biancofiore, Nicholas Favalli, Emanuele Puca, Sebastian Oehler, Dario Neri, Samuele Cazzamalli   +12 more
wiley   +1 more source

Recent Advances in the Chemical Pathology of Alkaline PhosPhatase [PDF]

, 1964
D. W. Moss
openalex   +1 more source

Persistent elevations of alkaline phosphatase as an early indicator of GM1 gangliosidosis. [PDF]

Mol Genet Metab Rep
Menkovic I, Williams M, Makhijani N, Wei R, Young SP, El-Gharbawy A, Stiles AR.   +6 more
europepmc   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

Advanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen   +7 more
wiley   +1 more source