Results 21 to 30 of about 331,716 (307)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
مجله علمی دانشگاه علوم پزشکی کردستان, 2023 Background and Aim: Evaluation of the alkaline phosphatase expression is known as one of the diagnostic markers to confirm the stem cells differentiation into osteoblasts.
Samaneh Harimi +3 more
doaj
Hypophosphatasia in Taiwan: Report of Two Cases
Kaohsiung Journal of Medical Sciences, 2005 Hypophosphatasia is a rare inherited metabolic disease characterized by rickets with reduced plasma and tissue alkaline phosphatase activity. It may be present in infancy, childhood, or adulthood.
Yen-Yin Chou +2 more
doaj +1 more source
Prevalence of hypovitaminosis D in exclusive breastfed babies in first 6 months of life
Al-Azhar Assiut Medical Journal, 2023 Background and Aim Due to all its beneficial effects on child survival, exclusive breastfeeding is recommended up to the age of 6 months. Human milk is an animal type’s explicit eating routine with an even nourishing profile, microbiologically safe ...
Yasser A. Ahmed +3 more
doaj +1 more source
Alkaline Phosphatase Isoenzymes
Enzyme, 1975 Abstract The human alkaline phosphatases constitute a system of multiple molecular forms of enzymes in which heterogeneity is partly due to genetic factors and partly to posttranslational modifications. Recognition of the nature and occurrence of these multiple forms has made a significant contribution both to the understanding of ...
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Clinical application experience of asfotase alfa for a young patient with childhood hypophosphatasia
Остеопороз и остеопатии, 2019 Hypophosphatasia (HPP) is a rare hereditary metabolic disease characterized by defective bone and dental mineralization, systemic complications that lead to disability of patients.
Nataliya Y. Kalinchenko +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Predictive factors of late cholangitis in patients undergoing pancreaticoduodenectomy
World Journal of Surgical Oncology, 2018 Background Because the survival rate for patients experiencing late complications after pancreaticoduodenectomy (PD) is increasing, late complications should receive as much attention as early complications do. Methods Between April 2007 and August 2016,
Yasuhiro Ito +4 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source