Results 21 to 30 of about 333,892 (266)

Beryllium and Alkaline Phosphatase [PDF]

open access: yesNature, 1950
RECENTLY, two papers1,2 have appeared in which it has been shown that beryllium inhibits alkaline phosphatase by competition with magnesium. However, as inhibitions of more than 60 per cent were rarely attained, the results are of qualitative interest only.
openaire   +2 more sources

COMPARISON OF METHODS FOR ALKALINE PHOSPHATASE AND PEROXIDASE DETECTION IN MILK

open access: yesRevista do Instituto de Latícinios Cândido Tostes, 2014
This study evaluated the performance of strips for colorimetric detection of alkaline phosphatase and peroxidase in milk, comparing them with a kit of reagents for alkaline phosphatase and the official methodology for peroxidase.
felipe Nael Seixas   +5 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Alkaline Phosphatase and Cholestasis [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1986
The process of cholestasis in both man and rat leads in the majority of cases to the appearance of a biliary band in the electrophoresis of alkaline phosphatase isoenzymes. In this article, the biochemical nature and mode of formation of the biliary band is discussed, with reference to its appearance in cholestasis and other hepatobiliary diseases.
R W, Wulkan, B, Leijnse
openaire   +2 more sources

Alkaline Phosphatase in Stem Cells

open access: yesStem Cells International, 2015
Alkaline phosphatase is an enzyme commonly expressed in almost all living organisms. In humans and other mammals, determinations of the expression and activity of alkaline phosphatase have frequently been used for cell determination in developmental ...
Kateřina Štefková   +2 more
doaj   +1 more source

Hypophosphatasia in Taiwan: Report of Two Cases

open access: yesKaohsiung Journal of Medical Sciences, 2005
Hypophosphatasia is a rare inherited metabolic disease characterized by rickets with reduced plasma and tissue alkaline phosphatase activity. It may be present in infancy, childhood, or adulthood.
Yen-Yin Chou   +2 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Synthesis, kinetic studies and in-silico investigations of novel quinolinyl-iminothiazolines as alkaline phosphatase inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
Deposition of hydroxyapatite (HA) or alkaline phosphate crystals on soft tissues causes the pathological calcification diseases comprising of end-stage osteoarthritis (OA), ankylosing spondylitis (AS), medial artery calcification and tumour calcification.
Muhammad Naeem Mustafa   +10 more
doaj   +1 more source

Elevated Liver Enzymes Is Not an Impediment to Allopurinol Dose Escalation: An Observational Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Routine liver enzyme monitoring is advocated for while on allopurinol, but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzyme levels in patients with gout commenced on allopurinol. Methods One hundred and fifty patients with gout and normal baseline serum aminotransferases initiated on ...
May Shuen Tang   +4 more
wiley   +1 more source

Alkaline Phosphatase

open access: yesEurasian Journal of Medicine, 2019
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Hüseyin T. Sessiz
doaj  

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