Gene duplication has been shown to drive molecular evolution, with dietary pressures expanding detoxification genes across species. In humans, CYP2D6 gene duplications enhance alkaloid and drug metabolism, reflecting ancient dietary adaptations. Similarly, tobacco‐feeding aphids amplify CYP6CY3 for nicotine and insecticide resistance, and as recently ...
Magnus Ingelman‐Sundberg
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Unlocking the Alkaloid Biological Potential of Chili Pepper (<i>Capsicum</i> spp.), Cacao (<i>Theobroma cacao</i> L.), and Coffee (<i>Coffea</i> spp.) Byproducts: Characterization, Non-Conventional Extraction, Applications, and Future Perspectives. [PDF]
Cárdenas A +3 more
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THE ECONOMICAL USE OF SOLUTIONS OF COSTLY ALKALOIDS FOR OPHTHALMIC PURPOSES [PDF]
N. B. Harman
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Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia +4 more
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Evaluation of the expression pattern of TIAs pathway genes in response to tryptophan amino acid treatment and drought stress in Catharanthus roseus. [PDF]
Yousefi F +5 more
europepmc +1 more source
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal +14 more
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Seasonal, Organ-, and Location-Dependent Variations in the Alkaloid Content of <i>Pachysandra terminalis</i> Investigated by Multivariate Data Analysis of LC-MS Profiles. [PDF]
Schäfer L, Sendker J, Schmidt TJ.
europepmc +1 more source
The Separation and Identification of Ergot Alkaloids by Paper Partition Chromatography [PDF]
G E Foster +2 more
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Emerging green extraction techniques are revolutionizing the recovery of bioactive compounds from sweet potato (Ipomoea batatas [L.] Lam) leaves. These approaches enhance the yield and stability of key phytochemicals like caffeoylquinic acids, flavonoids, and polyphenols, which offer potent antioxidants, anti‐inflammatory, and metabolic health benefits.
M. H. A. Jahurul, S. Islam
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