ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen +7 more
wiley +1 more source
Phytochemistry, Bioactivity, and Toxicological Duality of <i>Oxytropis glabra</i> DC: A Review. [PDF]
Raganina K +11 more
europepmc +1 more source
Agesamines A and B, New Dibromopyrrole Alkaloids from the Sponge Agelas sp.
Sachiko Tsukamoto +5 more
openalex +1 more source
Alkaloids from the Mangrove-Derived Actinomycete Jishengella endophytica 161111 [PDF]
Pei Wang +6 more
openalex +1 more source
Poly(sarcosine) Lipid Synthesis From CO2‐Based Sarcosine‐N‐Carboxyanhydride
In this work, we optimize and scale‐up a CO2‐based synthesis of sarcosine‐N‐carboxyanhydride (Sar‐NCA) to the gram scale. The low toxicity and simplicity of the approach make it an attractive alternative to current toxic phosgene‐based approaches. The CO2‐based Sar‐NCA has sufficient purity for controlled polymerization.
Florian T. Kaps +7 more
wiley +1 more source
Metabolic profiling and pharmacological evaluation of alkaloids in three <i>Murraya</i> species. [PDF]
Huang H +8 more
europepmc +1 more source
Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke +2 more
wiley +1 more source
<i>Fritillaria pallidiflora</i> Schrenk ex Fisch. & C.A.Mey. (Yi Beimu): Ethnopharmacology, Phytochemistry, Pharmacological Insights, and Future Prospects. [PDF]
Aierken K, Li J, Waheed A.
europepmc +1 more source
Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research
ABSTRACT Ambient and direct mass spectrometry (MS) methods are becoming increasingly used for the rapid analysis of food, beverage and agricultural samples. Novel ionization approaches combined with targeted, or untargeted workflows provide analytical outcomes within a greatly reduced time period compared to traditional separation science coupled with ...
Leigh M. Schmidtke +3 more
wiley +1 more source
Pharmacological Potential of Peruvian <i>Eustephia</i> Species (Amaryllidaceae): Alkaloid Diversity, Cholinesterase Inhibition, and Anti-<i>Trypanosoma cruzi</i> Activity. [PDF]
Llalla-Cordova O +10 more
europepmc +1 more source

