Results 111 to 120 of about 157,429 (315)
N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions
Chemistry – A European Journal, EarlyView.Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero +8 more
wiley +1 more source
Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9
Cytoskeleton, EarlyView.ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook +2 more
wiley +1 more source
Chemodiversity, chemotaxonomy and chemoecology of Amaryllidaceae alkaloids
The Amaryllidaceae alkaloids are a distinctive chemotaxonomic feature of the subfamily Amaryllidoideae of the family Amaryllidaceae, which consists of 59 genera and > 800 species distributed primarily in tropical and subtropical areas.
Osorio Durango, Edison Javier +3 more
core +1 more source
Drug Testing and Analysis, EarlyView.In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe +5 more
wiley +1 more source
The Alkaloids of the Madangamine Group
This chapter is focused on madangamines, a small group of complex diamine alkaloids isolated from marine sponges of the order Haplosclerida, and covers their isolation, characterization, biogenesis, biological activity, and synthesis.
Proto, Stefano +4 more
core +1 more source
Biologically active alkaloids from Alstonia angustiloba / Ku Wai Foong [PDF]
, 2011 The alkaloidal content of Malaysian plant, Alstonia angustiloba Miq., was investigated and the results are summarized as below (Table). A total of 20 alkaloids were isolated and characterized, of which, three were new alkaloids, viz., angustilobine C (1),
Ku, Wai Foong
core
Drug Testing and Analysis, EarlyView.An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis +5 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Pilocarpine And Related Alkaloids In Pilocarpus Vahl (rutaceae) [PDF]
, 2015 Pilocarpine is mainly known as a drug for the treatment of glaucoma and it is also used as a stimulant of sweat and lachrymal glands. Species of the genus Pilocarpus are collectively named jaborandi in Brazil and their leaves are the only known source of
Eberlin M.N. +4 more
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European Journal of Organic Chemistry, EarlyView.1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer +6 more
wiley +1 more source