Results 51 to 60 of about 19,243 (206)

AltitudeOmics : Resetting of Cerebrovascular CO2 Reactivity Following Acclimatization to High Altitude. [PDF]

, 2015
Previous studies reported enhanced cerebrovascular CO2 reactivity upon ascent to high altitude using linear models. However, there is evidence that this response may be sigmoidal in nature.
Duffin, J., Fan, J.L., Kayser, B., Lovering, A.T., Roach, R.C., Subudhi, A.W.   +5 more
core   +1 more source

Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures [PDF]

, 2013
Peer ...
Blaesse, Peter, El Muayed, Malek, Helmy, Mohamed, Hennings, J. Christopher, Huebner, Antje K., Hübner, Christian A., Kaila, Kai, Kang, Hyo Jung, Kirilkin, Ilya, Ruusuvuori, Eva, Sestan, Nenad, Voipio, Juha, Yukin, Alexey Y.   +12 more
core   +2 more sources

Study on biochemical findings and status of acid-base disorder among the patients attending Nobel Medical College Teaching Hospital.

Journal of Nepal Medical Association, 2019
Introduction: Acid base disorder is a condition characterized by alteration in blood pH by the imbalance between the components of blood leading to a life threatening situation.
Rupesh Kumar Shreewastav, Krishna Pokhrel, Madan Pandey, Ganesh Prasad Singh, Arambam Giridhari Singh   +4 more
doaj   +1 more source

Hypertrophic pyloric stenosis [PDF]

, 2013
A 6-week old baby was brought to A&E by her parents, after a 3 week history of frequent vomiting, not tolerating feeds, and weight loss. She was well for the first 3 weeks of life, before she stopped tolerating any feeds. Despite several changes with the
Tabone, Trevor, Vella Baldacchino, Andrea   +1 more
core  

Carbonic anhydrase inhibitors in patients with respiratory failure and metabolic alkalosis: a systematic review and meta-analysis of randomized controlled trials

Critical Care, 2018
Background Metabolic alkalosis is common in patients with respiratory failure and may delay weaning in mechanically ventilated patients. Carbonic anhydrase inhibitors block renal bicarbonate reabsorption, and thus reverse metabolic alkalosis.
Bassem Y Tanios, Maryam O Omran, Carlos Noujeim, Tamara Lotfi, Samir S Mallat, Pierre K Bou-Khalil, Elie A Akl, Houssam S Itani   +7 more
doaj   +1 more source

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay, Saptarshi Mukerji, Bengt Kayser, Jui‐Lin Fan   +3 more
wiley   +1 more source

Vagal TRPV1 activation exacerbates thermal hyperpnea and increases susceptibility to experimental febrile seizures in immature rats

Neurobiology of Disease, 2018
Thermal hyperpnea, a pattern of breathing during hyperthermia that is characterized by an increase in tidal volume as well as breathing frequency, is known to lead to respiratory alkalosis.
Karlene T. Barrett, Arijit Roy, Keelin B. Rivard, Richard J.A. Wilson, Morris H. Scantlebury   +4 more
doaj   +1 more source

Ventilatory and cerebrovascular responses to exercise in lowlander children acclimatizing to high‐altitude

The Journal of Physiology, EarlyView.
Abstract figure legend To investigate age‐related differences in ventilatory and cerebrovascular responses to exercise at high‐altitude, adults (n = 10, 23–44 years) and children (n = 8, 7–14 years) completed progressive cycling exercise tests at sea‐level and following 6 days of acclimatization at 3800 m.
J. L. Koep, M. G. Rieger, K. J. Smith, G. R. DuManoir, C. M. Tallon, D. R. Perkins, S. Piombo, M. Stembridge, D. M. Cooper, S. Radom‐Aizik, P. N. Ainslie, A. M. McManus   +11 more
wiley   +1 more source

Elevated carotid body tonic activity contributes to ventilatory acclimatization and de‐acclimatization to high altitude at rest and during exercise

The Journal of Physiology, EarlyView.
Abstract figure legend Participants spent 13 days at high altitude (3800 m), where the reduced inspired oxygen pressure (↓PiO2$ \downarrow {P_{{\mathrm{i}}{{\mathrm{O}}_2}}}$) which elicited ventilatory acclimatization and increased inhibition of ventilation by transient hyperoxia (ΔV̇E$\Delta {\dot V_{\mathrm{E}}}$).
Ayechew A. Getu, L. Madden Brewster, Travis D. Gibbons, James D. Anholm, Michael Stembridge, Philip N. Ainslie, Jay M. J. R. Carr   +6 more
wiley   +1 more source

Effect of varying driving pressure and respiratory rate on ventilator‐induced lung injury in healthy and injured lungs: An experimental animal study

The Journal of Physiology, EarlyView.
Abstract figure legend Top: experimental groups for the two series of rats: five combinations of driving pressure (DP) and respiratory rate (RR), maintaining a constant 4DP+RR value of 140, were applied for 4 h in healthy lungs (Series 1) and 2 h in HCl‐injured lungs (Series 2).
Davide Raimondi Cominesi, Vanessa Zambelli, Emma J. Murphy, Roberta Garberi, Aurora Magliocca, Roberto Fumagalli, Giacomo Bellani, Giuseppe Foti, Maurizio Cereda, John G. Laffey, Emanuele Rezoagli   +10 more
wiley   +1 more source