Results 41 to 50 of about 10,203 (251)

RecA stimulates AlkB-mediated direct repair of DNA adducts [PDF]

open access: yesNucleic Acids Research, 2016
The Escherichia coli AlkB protein is a 2-oxoglutarate/Fe(II)-dependent demethylase that repairs alkylated single stranded and double stranded DNA. Immunoaffinity chromatography coupled with mass spectrometry identified RecA, a key factor in homologous recombination, as an AlkB-associated protein.
Shivange, Gururaj   +4 more
openaire   +3 more sources

Electrochemical Hydroxylation of C3–C12 n-Alkanes by Recombinant Alkane Hydroxylase (AlkB) and Rubredoxin-2 (AlkG) from Pseudomonas putida GPo1

open access: yesScientific Reports, 2017
An unprecedented method for the efficient conversion of C3–C12 linear alkanes to their corresponding primary alcohols mediated by the membrane-bound alkane hydroxylase (AlkB) from Pseudomonas putida GPo1 is demonstrated. The X-ray absorption spectroscopy
Yi-Fang Tsai   +8 more
doaj   +1 more source

1,N 6 -α-hydroxypropanoadenine, the acrolein adduct to adenine, is a substrate for AlkB dioxygenase [PDF]

open access: yes, 2017
1,N6-α-hydroxypropanoadenine (HPA) is an exocyclic DNA adduct of acrolein – an environmental pollutant and endocellular oxidative stress product. Escherichia coli AlkB dioxygenase belongs to the superfamily of α-ketoglutarate (αKG)- and iron-dependent ...
Dylewska, Małgorzata   +4 more
core   +1 more source

YAMAT-seq: an efficient method for high-throughput sequencing of mature transfer RNAs. [PDF]

open access: yes, 2017
Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in various biological pathways and exhibit highly variable expression profiles.
Honda, Shozo   +5 more
core   +2 more sources

M. tuberculosis AlkX Encoded by rv3249c Regulates a Conserved Alkane Hydroxylase System That Is Important for Replication in Macrophages and Biofilm Formation

open access: yesMicrobiology Spectrum, 2022
Mycobacterium tuberculosis is a highly specialized human pathogen. The success of M. tuberculosis is due to its ability to replicate within host macrophages, resist host immune responses, and ultimately enter a persistent state during a latent ...
Haley Stokas   +5 more
doaj   +1 more source

Marine crude-oil biodegradation: a central role for interspecies interactions [PDF]

open access: yes, 2012
The marine environment is highly susceptible to pollution by petroleum, and so it is important to understand how microorganisms degrade hydrocarbons, and thereby mitigate ecosystem damage. Our understanding about the ecology, physiology, biochemistry and
Folwell, Benjamin D   +3 more
core   +1 more source

Structural and mechanistic studies of AlkB

open access: yesThe FASEB Journal, 2008
Recently, there has been rapid progress in understanding the molecular functions of DNA repair enzymes in the AlkB superfamily, which are present in many eubacteria and all higher eukaryotes. These enzymes have been demonstrated to catalyze direct repair of adenine and cytosine bases that have been alkylated on endocyclic nitrogen ...
John Francis Hunt   +8 more
openaire   +1 more source

Distribution of alkB genes within n-alkane-degrading bacteria [PDF]

open access: yesJournal of Applied Microbiology, 2000
Fifty-four bacterial strains belonging to 37 species were tested for their ability to assimilate short chain and/or medium chain liquid n-alkanes. A gene probe derived from the alkB gene of Pseudomonas oleovorans ATCC 29347 was utilized in hybridization experiments.
A, Vomberg, U, Klinner
openaire   +2 more sources

Enhanced production of alkane hydroxylase from Penicillium chrysogenum SNP5 (MTCC13144) through feed-forward neural network and genetic algorithm

open access: yesAMB Express, 2022
Alkane hydroxylase (AlkB), a membrane-bound enzyme has high industrial demand; however, its economical production remains challenging due to its intrinsic nature and co-factor dependency.
Satyapriy Das, Sangeeta Negi
doaj   +1 more source

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