Results 41 to 50 of about 10,203 (251)
RecA stimulates AlkB-mediated direct repair of DNA adducts [PDF]
The Escherichia coli AlkB protein is a 2-oxoglutarate/Fe(II)-dependent demethylase that repairs alkylated single stranded and double stranded DNA. Immunoaffinity chromatography coupled with mass spectrometry identified RecA, a key factor in homologous recombination, as an AlkB-associated protein.
Shivange, Gururaj +4 more
openaire +3 more sources
An unprecedented method for the efficient conversion of C3–C12 linear alkanes to their corresponding primary alcohols mediated by the membrane-bound alkane hydroxylase (AlkB) from Pseudomonas putida GPo1 is demonstrated. The X-ray absorption spectroscopy
Yi-Fang Tsai +8 more
doaj +1 more source
1,N 6 -α-hydroxypropanoadenine, the acrolein adduct to adenine, is a substrate for AlkB dioxygenase [PDF]
1,N6-α-hydroxypropanoadenine (HPA) is an exocyclic DNA adduct of acrolein – an environmental pollutant and endocellular oxidative stress product. Escherichia coli AlkB dioxygenase belongs to the superfamily of α-ketoglutarate (αKG)- and iron-dependent ...
Dylewska, Małgorzata +4 more
core +1 more source
YAMAT-seq: an efficient method for high-throughput sequencing of mature transfer RNAs. [PDF]
Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in various biological pathways and exhibit highly variable expression profiles.
Honda, Shozo +5 more
core +2 more sources
Mycobacterium tuberculosis is a highly specialized human pathogen. The success of M. tuberculosis is due to its ability to replicate within host macrophages, resist host immune responses, and ultimately enter a persistent state during a latent ...
Haley Stokas +5 more
doaj +1 more source
Marine crude-oil biodegradation: a central role for interspecies interactions [PDF]
The marine environment is highly susceptible to pollution by petroleum, and so it is important to understand how microorganisms degrade hydrocarbons, and thereby mitigate ecosystem damage. Our understanding about the ecology, physiology, biochemistry and
Folwell, Benjamin D +3 more
core +1 more source
Structural and mechanistic studies of AlkB
Recently, there has been rapid progress in understanding the molecular functions of DNA repair enzymes in the AlkB superfamily, which are present in many eubacteria and all higher eukaryotes. These enzymes have been demonstrated to catalyze direct repair of adenine and cytosine bases that have been alkylated on endocyclic nitrogen ...
John Francis Hunt +8 more
openaire +1 more source
Distribution of alkB genes within n-alkane-degrading bacteria [PDF]
Fifty-four bacterial strains belonging to 37 species were tested for their ability to assimilate short chain and/or medium chain liquid n-alkanes. A gene probe derived from the alkB gene of Pseudomonas oleovorans ATCC 29347 was utilized in hybridization experiments.
A, Vomberg, U, Klinner
openaire +2 more sources
Alkane hydroxylase (AlkB), a membrane-bound enzyme has high industrial demand; however, its economical production remains challenging due to its intrinsic nature and co-factor dependency.
Satyapriy Das, Sangeeta Negi
doaj +1 more source

