Results 151 to 160 of about 1,546 (186)
Journal of Gastroenterology and Hepatology, 2018 AbstractBackground and AimThe mammalian AlkB homolog protein family has been reported to promote tumor cell invasion and metastasis of human cancer. However, the expression status and clinical significance of AlkB homolog 3 (ALKBH3) in hepatocellular carcinoma (HCC) have not been reported yet.MethodsIn the present study, we investigated the protein ...
Qian Wang +4 more
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alkB homologs in thermophilic bacteria of the genus Geobacillus
Molecular Biology, 2008 Screening of alkane hydroxylase genes (alkB) was performed in the thermophilic aerobic bacteria of the genus Geobacillus. Total DNA was extracted from the biomass of 11 strains grown on the mixture of saturated C10-C20 hydrocarbons, PCR amplification of fragments of alkB genes was performed with degenerate oligonucleotide primers, PCR products were ...
T. P. Tourova +6 more
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Pathology - Research and Practice, 2023 The oncogenic role of circPUM1 has been revealed in multiple cancers. Nevertheless, the specific role and molecular mechanism of circPUM1 in neuroblastoma (NB) have never been reported.The expression of genes was detected using RT-qPCR and Western Blot assay.
Lin Liu +9 more
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Anti-Tumor Effect of AlkB Homolog 3 Knockdown in Hormone- Independent Prostate Cancer Cells
Current Cancer Drug Targets, 2012 Castrate resistant prostate cancer (CRPC) is a disease that is resistant to both hormone therapy and chemotherapy. At present, no curative therapy for CRPC has been established. Therefore, it is necessary to determine a novel molecular target for the development of therapeutic agents.
Kazuo Koike +14 more
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AlkB homologs in metazoans – an applied bioinformatics and experimental DNA/RNA repair study
, 2015 Abstract E. coli AlkB protein was discovered three decades ago and is known to be involved in direct damage reversal of methylation lesions in DNA and RNA through oxidative demethylation. The protein belongs to the superfamily of 2-oxoglutarate and Fe(II)-dependent dioxygenases. Nine mammalian homologs of AlkB, ALKBH1-8 and FTO have been identified. In
Roza Berhanu Lemma
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Human Cell, 2020 Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignancies worldwide. miR-193a-3p acts as an oncogene or tumor suppressor in different cancers. However, the functional role and regulatory mechanism of miR-193a-3p in ESCC remain to be elucidated.
Jinliang Xue +3 more
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The FASEB JournalABSTRACT Endometriosis is a common gynecological endocrine disease with unclear pathogenesis. Evidence suggests enhanced aerobic glycolysis in ectopic endometrium of endometriosis. The role of N6‐methyladenosine (m6A) modification in female reproductive diseases has been revealed in recent years, and it is involved in the regulation ...
Junjun Liu +8 more
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Journal of Microbiological Methods, 2006
An improved method was developed that allowed the specific detection of the gene alkB (coding for the rubredoxin dependent alkane monooxygenase) from bacteria without any obvious strain specific discrimination using a combination of PCR and hybridization.
Karin, Kloos +2 more
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An improved method was developed that allowed the specific detection of the gene alkB (coding for the rubredoxin dependent alkane monooxygenase) from bacteria without any obvious strain specific discrimination using a combination of PCR and hybridization.
Karin, Kloos +2 more
openaire +2 more sources
Biology of ReproductionAbstract The risk of multiple placental thrombosis is significantly elevated in preeclampsia, and the vascular endothelium plays a vital role in coagulation processes through the secretion of Integrin alpha 2b, von Willebrand factor, and tissue factor. However, the underlying pathological mechanisms remain unclear.
Yingying Zhang +10 more
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