Results 71 to 80 of about 110,088 (171)
Arthritis &Rheumatology, Volume 77, Issue 4, Page 423-438, April 2025.Objective Myeloid‐derived suppressor cells (MDSCs) contribute to the pathogenesis of systemic lupus erythematosus (SLE), in part due to promoting the survival of plasma cells. FoxO1 expression in monocytic MDSCs (M‐MDSCs) exhibits a negative correlation with the SLE Disease Activity Index score.
Liping Tan +6 more
wiley +1 more source
Homological Descent for Motivic Homology Theories [PDF]
arXiv, 2014 We show that motivic homology, motivic Borel-Moore homology and higher Chow groups satisfy homological descent for hyperenvelopes, and l-hyperenvelopes after inverting l.
arxiv
Lactylation of HDAC1 Confers Resistance to Ferroptosis in Colorectal Cancer
Advanced Science, Volume 12, Issue 12, March 27, 2025.HDAC inhibitor decreases HDAC1K412 lactylation to sensitize colorectal cancer to ferroptosis and the combination of HDAC inhibitor and ferroptosis inducers can be a promising therapeutic strategy for colorectal cancer. Abstract Colorectal cancer (CRC) is highly resistant to ferroptosis, which hinders the application of anti‐ferroptosis therapy. Through
Zhou Yang +17 more
wiley +1 more source
André-Quillen homology via functor homology [PDF]
arXiv, 2001 We obtain Andr\'e-Quillen homology for commutative algebras using relative homological algebra in the category of functors on finite pointed ...
arxiv
Cell Biology International, Volume 49, Issue 3, Page 288-302, March 2025.Abstract Mounting evidence indicates the involvement of N6‐methyladenosine (m6A) alterations in diverse neurological disorders and the activation of microglia. However, the role of m6A methyltransferase Wilms' tumor 1‐associated protein (WTAP) in regulating microglial polarization during ischemic stroke (IS) remains unknown. We performed bioinformatics
Haijing Sui +3 more
wiley +1 more source
Detection, molecular function and mechanisms of m5C in cancer
Clinical and Translational Medicine, Volume 15, Issue 3, March 2025.The role of m5C in cancers. The role of m5C regulators‐ writers, erasers, and readers‐ in various cancer types, including NSCLC, PCa, GC, AML, BCa, and HCC. Abstract Interest in RNA posttranscriptional modifications, particularly 5‐methylcytosine (m5C), has surged in recent years.
Linhui Zhang +6 more
wiley +1 more source
Excision in Hopf cyclic homology [PDF]
arXiv, 2005 In this paper we show that both variants of the Hopf cyclic homology has excision under some natural homological conditions on the objects and the coefficient module.
arxiv
A homological action on sutured instanton homology [PDF]
arXiv, 2023 We define a homological action on sutured instanton Floer homology. This action is well-defined up to scalars, and behaves well under connected sums and sutured manifold decompositions. As an application, we show that instanton knot homology detects link splitting for two-component links.
arxiv
Food Frontiers, Volume 6, Issue 2, Page 789-800, March 2025.ALKBH5 enhances PGK2 mRNA stability by inducing PGK2 m6A demethylation. PGK2 modulates protein phosphorylation to droved myofiber type transformation. PGK2 regulates hypoxanthine accumulation by mediating the phosphorylation of AMPD1. ABSTRACT Recent studies have found that the amount and proportion of meat flavor–related metabolites differ among ...
Manting Ma +6 more
wiley +1 more source
Reversal of DNA alkylation damage by two human dioxygenases
Proceedings of the National Academy of Sciences of the United States of America, 2002 The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the DNA lesions 1-methyladenine and 3-methylcytosine, which are generated in single-stranded stretches of DNA.
T. Duncan +5 more
semanticscholar +1 more source