Results 161 to 170 of about 29,164 (249)

Biosynthesis of the Fully Saturated C16 Homosesquiterpene Descartane Through Deprotonation With Cyclopropanation

Angewandte Chemie International Edition, EarlyView.
A non‐canonical C16 sesquiterpene synthase from Morganella morganii produces the unusual scaffold descartane. Its cyclisation mechanism was rationalised by isotopic labelling experiments and DFT calculations. Site‐directed mutagenesis altered enzyme function, resulting in alternative products, including voltairene, which requires a different ...
Kexin Yang, Philip Troycke, Bernd Goldfuss, Michael Groll, Jeroen S. Dickschat   +4 more
wiley   +1 more source

Enabling Fluoroalkyl-Sulfonylalkylation and Fluoroalkyl-Halogenation of Alkenes and Alkynes via Photoredox Catalysis. [PDF]

J Am Chem Soc
Hewa Inaththappulige SIN, Acharya A, Agampodi NDDZ, Singh H, Giri R.   +4 more
europepmc   +1 more source

Precise borylation of targeted methyl group via an orderly chain-walking strategy. [PDF]

Sci Adv
Bao Y, Hu C, Zheng L, Wu Y, Huang F, Lu Z.   +5 more
europepmc   +1 more source

Potassium <i>tert</i>-Butoxide-Mediated Isomerization of Alkenes: A Versatile Protocol for Miscellaneous Substrates. [PDF]

ACS Omega
Heras Martínez HM, Hampton SM, Isbel SR, MacFarlane CN, Aparicio EB, Blé-González EA, Bugarin A.   +6 more
europepmc   +1 more source

Overriding the radical polarity matching principle: selective chlorohydroxylation of electron-deficient alkenes enabled by Ce photocatalysis. [PDF]

Chem Sci
Ou L, Bai Y, Liu S, Kan Z, Lan Y, Zhu J, Liu S, Ren Z, Li SJ, Niu L.   +9 more
europepmc   +1 more source

Asymmetric synthesis of alkyl fluorides <i>via</i> biocatalytic reduction of α-fluoroenones and α-fluoroenoates.

Green Chem
Allan H, Wang Y, Winterson B, King A, Aliev AE, Szpara R, Laserna V, Coomber CE, Ward JM, Jeffries JWE, Hailes HC, Sheppard TD.   +11 more
europepmc   +1 more source

Bifunctional Lipid-Protein Cross-linking Efficiency and Reaction Products. [PDF]

J Am Chem Soc
Kirschbaum C, Lennartz HM, Cook KC, Böhlig K, Papangelis A, Robinson CV, Nadler A.   +6 more
europepmc   +1 more source

Photogenerated Oxetanes as a Gateway to Uphill Cyclopropanation

Angewandte Chemie International Edition, EarlyView.
An atom‐economical route to densely functionalized cyclopropanes from furans and photochemically activated aldehydes is enabled by a unique oxetane‐to‐cyclopropane rearrangement. These cyclopropanes can be used to access complex bioactive scaffolds and serve as a platform for asymmetric cyclopropane synthesis.
Tim Köglmeier, Thomas J. Tiefel, Oliver Reiser   +2 more
wiley   +1 more source

Electrochemically cooperative halogen-cation delivery enables modular electrophilic haloesterification of both activated and unactivated alkenes. [PDF]

Chem Sci
Xu HH, Qian DD, Fan Y, Zhang JJ, Guo CL, Xu HC.   +5 more
europepmc   +1 more source

Asymmetric Reduction of Unactivated Alkenes. [PDF]

Chemistry
Fessner ND, Roth S, Niese R, Müller M.
europepmc   +1 more source