Results 181 to 190 of about 52,647 (305)

Organic radical reactivity: activation and deactivation through alkyl substitution.

Phys Chem Chem Phys
Rodrigues Silva D, van der Schuur JM, Bickelhaupt FM.   +2 more
europepmc   +1 more source

PhSO₂CF₂H as a difluoromethylene bridge connecting electrophiles and electronically diverse alkenes. [PDF]

Chem Sci
Zhao Y, Zhu K, Zhao F, Zhang Y, Ni C, Hu J.   +5 more
europepmc   +1 more source

1,3‐Brook Rearrangement of α‐Silyl Allylic Alcohols: Copper‐Catalyzed Enantiospecific Formation of Allenes and Copper‐Mediated ipso‐Substitution Reactions Affording Trisubstituted Alkenes

Angewandte Chemie, EarlyView.
A regioselective ruthenium catalyzed trans‐hydrosilylation of propargyl alcohols followed by a 1,3‐Brook rearrangement opens access to reactive organocopper intermediates, which evolve upon warming into allenes with strict chirality transfer to the emerging axis; alternatively, these reactive species can be trapped with a large variety of electrophiles
Jack L. Sutro, Felix Anderl, Paul Haf‐Moths, Alois Fürstner   +3 more
wiley   +1 more source

Isolable C-Phosphonio-Boratavinyl Anion. [PDF]

Angew Chem Int Ed Engl
Xu H, Rodríguez-Álvarez A, Hossain MJ, Baceiredo A, Maerten E, Saffon-Merceron N, Branchadell V, Kato T.   +7 more
europepmc   +1 more source

Ring‐Retentive Allylation of Cyclopropanols Through Interception of Enolized Homoenolates by π‐Allylpalladium

Angewandte Chemie, EarlyView.
Cyclopropanols undergo palladium‐catalyzed, zinc‐mediated allylation with allyl acetates: the ring opens transiently to an enolized homoenolate, is intercepted by π‐allylpalladium, and recloses to furnish β‐allylated cyclopropanols. This formal “allylic cyclopropylation” broadens the reaction space for ring‐retentive functionalization of cyclopropanols.
Kento Tsukiji, Sena Miura, Naohiko Yoshikai   +2 more
wiley   +1 more source

Total Synthesis of Voratin C: Formation of the [6,5]-Spiroketal Core through Acid-Mediated Epoxide Cascade Opening. [PDF]

Org Lett
Ip CH, Ivlev S, Koert U.
europepmc   +1 more source

High‐Tg Polythioesters From Isomerization Ring‐Opening Polymerization of a Renewable Oxanorbornane‐Fused Thionolactone

Angewandte Chemie, EarlyView.
A biobased tricyclic thionolactone undergoes selective isomerization ring‐opening polymerization to yield a high‐molecular‐weight polythioester with an exceptionally high Tg of 171°C, exceeding that of the analogous polyester. The polythioester efficiently depolymerizes through backbiting, while its hydrolysis and methanolysis reveal the critical ...
Eva Harsevoort, Henk‐Jan Akkerman, Martin Lutz, Arnaud Thevenon, Pieter C. A. Bruijnincx   +4 more
wiley   +1 more source

Amine/ammonium buffering enables efficient anti-Markovnikov hydroamination of olefins with alkylamines. [PDF]

Nat Commun
Shen JY, Cheng JK, Wang Y, Yuan Z, Wang F.   +4 more
europepmc   +1 more source

Intramolecular Nickel‐Catalyzed Reductive Coupling: Enantioselective Synthesis of Tetrahydroisoquinolines and Related Heterocycles

Angewandte Chemie, EarlyView.
The successful extension of the nickel‐catalyzed asymmetric coupling of polarized 1,3‐dienes with aldehydes to an intramolecular setting opens an efficient new entry into hydroxylated N‐heterocyclic compounds, most notably valuable tetrahydroisoquinolines.
Thilo Bender, Markus Leutzsch, Yannik Sell, Alois Fürstner   +3 more
wiley   +1 more source

Flavin Catalysts in Organic Synthesis

Angewandte Chemie, EarlyView.
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley   +1 more source