Results 111 to 120 of about 196,557 (349)
Synthesis of functionalized polyisobutylene and its block copolymers with D,L-lactide
Журнал Белорусского государственного университета: Химия, 2019 Method of reactive polyisobutylene modification by various alkoxybenzenes (anisole and 4-phenoxybutanol) was proposed to form functionalized polyisobutylenes.
Pavel A. Nikishau +4 more
doaj +1 more source
Advanced Science, EarlyView.This study demonstrates significantly reduced Lkb1 expression in CD11c+ cells in chronic pancreatitis (CP) patients and animal models. Lkb1 deletion enhances CD11c+CD206+ macrophage infiltration and reprograms pancreatic stellate cells (PSCs) via OSM signaling.
Wenqing Zhang +10 more
wiley +1 more source
Donor–Acceptor Pentacene Analogues With Near‐Infrared Emission and Tunable Aromaticity
Angewandte Chemie, EarlyView.Air‐ and photostable heterocyclic pentacene analogues with donor and acceptor groups flanking a para‐quinodimethane core exhibit large dipole moments, narrow bandgaps, reversible redox behavior, and NIR‐I to NIR‐II absorption and emission with pronounced solvatochromism.
Krzysztof Nowak +6 more
wiley +2 more sources
Visible-Light-Promoted N-Alkylation Reactions of (aza)Aromatic Amines with Ethyl Diazoacetate [PDF]
, 2023 Yating Zhao +3 more
openalex +1 more source
Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance
Advanced Science, EarlyView.Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes +4 more
wiley +1 more source
Angewandte Chemie, EarlyView.A Pd‐catalyzed regioselective synthesis of benzylsilanols from Kobayashi‐type reagents has been developed through a mechanistically distinct approach involving 1,4‐Pd migration followed by intramolecular transmetalation. The reaction can be combined with various prior transition‐metal‐catalyzed processes and the resulting benzylsilanols have been ...
Ryo Shintani, Keisuke Tachibana
wiley +2 more sources
Molecular modelling and Function Prediction of hABH7, human homologue of _E. coli_ ALKB7 [PDF]
, 2011 Human homologues of ALKB protein have shown the prime role in DNA damaging drugs, used for cancer therapy. Little is known about structure and function of hABH7, one of the members of this superfamily. Therefore, in the present study we intend to predict
Ambarish Sharan Vidyarthi +2 more
core +1 more source
Protein processing characterized by a gel-free proteomics approach [PDF]
, 2008 We describe a method for the specific isolation of representative N-terminal peptides of proteins and their proteolytic fragments. Their isolation is based on a gel-free, peptidecentric proteomics approach using the principle of diagonal chromatography ...
A. Staes +17 more
core +1 more source
Advanced Science, EarlyView.This work overcomes the long‐standing challenge of hydrophilic modification of silicone rubber via a gradient polarity modification strategy. By constructing a hydrophilic interpenetrating network within cured SR, simultaneous surface‐to‐bulk modification is achieved while enabling monitoring through a Eu3+ complex fluorescent tracer.
Lihui Zhang +11 more
wiley +1 more source
Consequences of Medium‐Pore Zeolite Constraints for Alkene Cracking—The Case of n‐Pentene
Angewandte Chemie, EarlyView.Alkene cracking in medium‐pore zeolites is governed by a balance of enthalpic and entropic effects. Intrinsic barriers are quantified and shown to be lower than for alkanes due to stabilization of carbenium‐ion‐like transition states. Confinement and extra‐framework aluminum modulate reactivity by tuning transition‐state energetics, providing a ...
Ruixue Zhao +4 more
wiley +2 more sources