Results 171 to 180 of about 107,279 (237)

Cu(OTf)2-Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of Indoles with Arylidene Malonates Using Bis(sulfonamide)-Diamine Ligands

, 2013
Cu(OTf)2-Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of Indoles with Arylidene Malonates Using Bis(sulfonamide)-Diamine ...
吴凡, 王东平, 万伯顺, 吴静
core  

1,4‐Brook Rearrangement of β‐Silyl Allylic Alcohols: Trisubstituted Alkenes by Copper‐Mediated Stereoretentive ipso‐Substitution Reactions

Angewandte Chemie, EarlyView.
To fully leverage the power of the ruthenium‐catalyzed trans‐hydrosilylation of propargyl alcohols, it was necessary to develop a practical and robust method for the activation of those products that carry the silyl group distal to the hydroxy substituent.
Paul Haf‐Moths, Jack L. Sutro, Alois Fürstner   +2 more
wiley   +1 more source

Massively Parallel Profiling of Single-Cell RNA Dynamics Using Well-TEMP-seq. [PDF]

Curr Protoc
Wang D, Lv Q, Lin S.
europepmc   +1 more source

Electrocatalytic Polarity Inversion of Azlactones: Access to α‐Quaternary Amino Acids with Electron‐Rich SOMOphiles

Angewandte Chemie, EarlyView.
Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez, David Buedo, Alberto Vega‐Peñaloza, Kian Gosling, Stuart C. D. Kennington, Bart Limburg, Xavier Companyó   +6 more
wiley   +1 more source

Transient Boryl Assistance Enables Stereoselective Alkylation of Acyclic Tetrasubstituted Enolates. [PDF]

Angew Chem Int Ed Engl
Li JX, Zhuo WZ, Jiang MY, Lin Y, Zhu YS, Su B.   +5 more
europepmc   +1 more source

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +1 more source

Photoinduced Palladium-Catalyzed Site-Selective Meta-Alkylation of Pyridines. [PDF]

Angew Chem Int Ed Engl
Singh A, Kancherla R, Dutta S, Dey A, Pal K, Maity B, Kloene L, Cavallo L, Koenigs RM, Rueping M.   +9 more
europepmc   +1 more source

Modular Access to α‐Tertiary Amines: Electrochemical Tandem Di‐Functionalization of Olefins With Ammonia Surrogates and Amino Acids

Angewandte Chemie, EarlyView.
A metal‐ and oxidant‐free electrochemical multicomponent di‐functionalization strategy that rapidly converts 1,1‐disubstituted alkenes into α‐tertiary primary amines with simultaneous installation of bio‐relevant sulfur or selenium motifs was devised for late‐stage functionalization. ABSTRACT Quaternary carbon centers, especially those bearing nitrogen,
Adrija Ghosh, Tarun, Sven Erik Peters, Lutz Ackermann, Debasis Banerjee   +4 more
wiley   +1 more source

Redirecting Reaction Pathway in Tandem Catalysis With Isolated Metal-Acid Architecture. [PDF]

Angew Chem Int Ed Engl
Lang W, Sun K, Peng Z, Jia Y, Jia Y, Zhang L, Liu Z, Li L.   +7 more
europepmc   +1 more source

Glutaredoxins Rapidly Reduce Glutathione Hydroper‐ and Polysulfides

Angewandte Chemie International Edition, EarlyView.
Glutaredoxins (Grx) rapidly reduce glutathione polysulfides (GSSnSG) to glutathione hydroper/polysulfides (GSSnH) or GSSnH to hydrogen (poly)sulfides (H2Sn). Reduction of glutathionylated glutaredoxins by reduced glutathione (GSH) yields glutathione disulfide (GSSG).
Philipp Reinert, Seiryo Ogata, Laura Leiskau, Sernur Sena Yildiz, Takaaki Akaike, Uladzimir Barayeu, Marcel Deponte   +6 more
wiley   +1 more source