Results 161 to 170 of about 110,461 (301)

Extending Peptide Ligation to Acidic pH and Junctions Comprising Glycosylated and Phosphorylated Amino Acids

Angewandte Chemie International Edition, EarlyView.
A pyridine‐containing ligation auxiliary eliminates a major bottleneck of peptide ligation chemistry. The extended range of applicable pH values (2.0–7.5) in the ligation reaction helps to avoid epimerization. Native chemical ligation (NCL) proceeds at virtually any junction, including reactions at β‐branched amino acids, as well as O‐glycosylated or O‐
Sebastian Trunschke, Antonia Feida, Hendrik Hanebrink, Arseniy Galashov, Alina Herfort, Oliver Seitz   +5 more
wiley   +1 more source

Reactivity of Nitroarenes toward Alkyl Radicals Enables Direct C-H Alkylation. [PDF]

J Am Chem Soc
Das K, Chakraborty S, Paenurk E, König B.   +3 more
europepmc   +1 more source

Flocculation using selected cationic polymers reduces high‐risk host cell proteins in monoclonal antibody processes already during primary recovery

Biotechnology Progress, EarlyView.
Flocculation using cationic polymers leads to the creation of large floc complexes. Negative charged species like cells, cell debris, and negatively charged host cell impurities like host cell DNA and host cell proteins are trapped within the complex while the positively charged monoclonal antibody stays in solution.
Anna‐Carina Frank, Daniel Komuczki, Gregor Stitz, Timon Kalchmayr, Clemens Grünwald‐Gruber, Clara Hofmann, Natalie Deiringer, Christine Rösch, Peter Satzer, Rainer Hahn   +9 more
wiley   +1 more source

Cyanamide-Induced Desulfhydration Enables Access to α,β-Dehydropeptides. [PDF]

Org Lett
Yang Y, Xue S, Moreira R, van der Donk WA.   +3 more
europepmc   +1 more source

Advances in Sustainable Production of Bio‐Derived 5‐Alkoxymethylfurfural and Levulinate Esters: A Comprehensive Review

Carbon Energy, EarlyView.
The present review discusses the advancement in the catalytic synthesis of 5‐alkoxymethylfurfural (AMF) and levulinate esters (LEs) from the aspects of catalytic systems, reaction mechanisms, product isolation, and techno‐economic analysis, supplying valuable insights toward future sustainable and efficient manufacture of AMF and LEs. ABSTRACT The huge
Jun Zhang, Chunxiang Yang, Yuhe Liao, Jiawei Wang, Chengyu Li, Rui Shan, Haoran Yuan   +6 more
wiley   +1 more source

Redox-Neutral Vicinal Dialkylation of Aryl Boronic Esters via the Palladium/Norbornene Cooperative Catalysis. [PDF]

Angew Chem Int Ed Engl
Ye R, He P, Kan L, Plambeck TR, Dong G.
europepmc   +1 more source

The Impact of Glycation on Protein Digestibility

ChemFoodChem, EarlyView.
Schematic overview of how protein glycation affects digestibility and downstream nutritional consequences. Glycation‐derived structural modifications reduce protease accessibility, leading to limited hydrolysis and altered peptide generation. These changes decrease amino acid bioavailability and may subsequently contribute to microbiome alterations ...
Lea Hönemann, Simone Lipinski, Jana Raupbach   +2 more
wiley   +1 more source

The Catalytic Asymmetric Alkylation of Olefins with Alcohol Derivatives. [PDF]

J Am Chem Soc
Debie LM, Gotta T, Turberg M, Nöthling N, List B.   +4 more
europepmc   +1 more source

When Two Dimensions Matter: A Critical Review of Recent Comprehensive Two‐Dimensional Gas Chromatography Applications in Food Analysis

ChemFoodChem, EarlyView.
Comprehensive two‐dimensional gas chromatography (GC×GC) is gaining importance in food analysis, particularly for volatile and aroma‐related compounds. This review examines recent applications across plant‐, animal‐, and other food matrices, revealing trends in sample preparation, column selection, modulation and detection, while highlighting ...
Ana Jano, Alba Bautista, Ana M. Ares, José Bernal   +3 more
wiley   +1 more source

Deprotective Alkylation: A Platform for Alcohol-to-Amine Interconversion Using Nonafluoromesitylenesulfonamides. [PDF]

Angew Chem Int Ed Engl
Brześkiewicz J, Kapur K, Maryasin B, Maulide N.   +3 more
europepmc   +1 more source