Results 141 to 150 of about 196,557 (349)
Beilstein Journal of Organic Chemistry, 2019 4-Oxoquinolines are a class of organic substances of great importance in medicinal chemistry, due to their biological and synthetic versatility. N-1-Alkylated-4-oxoquinoline derivatives have been associated with different pharmacological activities such ...
Pedro N. Batalha +7 more
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RaPID Selection of Backbone Macrocyclic Peptides Targeting Akt2
Angewandte Chemie, EarlyView.Backbone macrocyclic peptide library (BMP) library was screened against Akt2 via RaPID to discover potent BMPPakti‐3 (IC50 = 34 nM). ABSTRACT Backbone‐cyclic peptides (BMPs) are an attractive class of molecules appeared in diverse natural bioactive products. However, mRNA display technology coupled with ribosomal synthesis is intrinsically inapplicable
Koki Shinbara +4 more
wiley +2 more sources
Beilstein Journal of Organic Chemistry, 2018 Traditional, established palladium cross-coupling procedures are widely applied in complex molecule synthesis; however, there is a significant disadvantage in the requirement for pre-functionalised substrates (commonly halides/triflates).
Andrew Kenny +5 more
doaj +1 more source
Mechanically Activated Luminescence in Polyurethanes Incorporating Calixarene Mechanophores
Angewandte Chemie, EarlyView.The conformational flexibility of a calix[4]arene is exploited to obtain a reversible mechanoluminophore featuring a pyrene excimer couple at the upper rim. Stretching a linear polyurethane incorporating such mechanophore results in luminescence color change from yellow–green to blue, consistent with a force‐induced conformational motion of the ...
Lucia Visieri +3 more
wiley +2 more sources
Simple synthesis of pyrrolo[3,2-e]indole-1-carbonitriles
Beilstein Journal of Organic Chemistry, 2013 Alkylation of 5-nitroindol-4-ylacetonitriles with ethyl chloroacetate, α-halomethyl ketones, and chloroacetonitrile followed by a treatment of the products with chlorotrimethylsilane in the presence of DBU gives 1-cyanopyrrolo[3,2-e]indoles substituted ...
Adam Trawczyński +3 more
doaj +1 more source
ALKYLATION OF POLYMER-BOUND α-CARBANION OF β-KETOSULFONE [PDF]
, 1989 Qisheng Ren +4 more
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A study of bonding between glass and plastic in glass-reinforced plastics - Phase II QUARTERLY progress report no. VI, 1 May - 31 Jul. 1965 [PDF]
Direct bond formation between glass and plastic in glass-reinforced plastic materials - alkylation of surface-based silicon atoms for producing Si-R ...
Chamberlain, D. L., Jr.
core +1 more source
Direct trifluoroethylation of carbonyl sulfoxonium ylides using hypervalent iodine compounds
Beilstein Journal of Organic ChemistryA novel study on the hypervalent iodine-mediated polyfluoroalkylation of sulfoxonium ylides was developed. Sulfoxonium ylides, known for their versatility and stability, are promising substrates for numerous transformations in synthetic chemistry.
Radell Echemendía +4 more
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Stereoselective Decarboxylative Alkylation of Titanium(IV) Enolates with Diacyl Peroxides [PDF]
, 2019 Alejandro Gómez‐Palomino +9 more
openalex +1 more source