Results 231 to 240 of about 166,984 (347)

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren   +7 more
wiley   +1 more source

Comparison of In‐Gel and SP3 Based Sample Preparation Protocols for LC‐MS/MS Based Proteomics

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Sensitivity, robustness, and reproducibility of sample preparation are main determinants of data quality in bottom‐up mass spectrometry‐based proteomics. To this end, in‐gel protein clean‐up and digestion has been used for decades and is characterized by its robustness and compatibility with harsh lysis conditions.
Luisa Schwarzmüller   +5 more
wiley   +1 more source

The N‐Glycome to Differentiate Mesenchymal Stem Cells Upon Chondrogenic Differentiation, Dedifferentiation, and Senescence

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir   +4 more
wiley   +1 more source

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà   +10 more
wiley   +1 more source

Proteomic Profiling Using a Proximity Extension Assay Panel on Serum Samples Stored at −25°C Over Several Decades

open access: yesPROTEOMICS, EarlyView.
ABSTRACT The advent of proteomics assays that provide accurate levels of thousands of proteins from relatively small sample volumes opens possibilities for biomarker research in biobanks with valuable samples. In this study, we leverage the applicability of the Olink proximity extension assay to profile serum samples of the Janus Serum Bank, which have
Steffan Daniel Bos   +4 more
wiley   +1 more source

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