Results 231 to 240 of about 196,557 (349)

Stereoselective Total Synthesis of (+)-Giganin and Its C10 Epimer by Using Late-Stage LithiationBorylation Methodology [PDF]

, 2013
Alali, Bandur, Beckmann, Besong, Blakemore, Crimmins, Curran, Davoli, De Luca, Dearden, Debré, Dixon, Donohoe, Donohoe, Duret, Duval, Elford, Esposti, Fang, Furuhata, Gao, Gralla, Griggs, Hattori, Hiscox, Hoppe, Hu, Hu, Huh, Kolb, Larouche-Gauthier, Liu, Marshall, Matteson, Matteson, Matteson, Matteson, Matteson, McLaughlin, Miyoshi, Oasa, Oberlies, Okun, Persich, Sohn, Strand, Strand, Strand, Stymiest, Takahashi, Takahashi, Takahashi, White, Yamamoto, Ye, Yu   +55 more
core   +3 more sources

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Discovery and Characterization of Divarasib (GDC-6036), a Potent Covalent Inhibitor of KRAS G12C. [PDF]

J Med Chem
Endres NF, Do S, Mroue R, Terrett JA, Saabye M, Oh A, Hunsaker T, Chan E, Tran JC, Nguyen LK, Lian Q, Ma TP, Garner T, Gerosa L, Beresini M, Boudreau A, Bronner SM, Cyr P, Ishisoko N, Izrayelit Y, Jiang F, Kellar T, La H, Labadie S, Lardy M, Liu L, Liu W, Miller S, Rudolph J, Plise E, Sellers BD, Shao C, Wang W, Wang Y, Wei W, Wong S, Yu C, Yu K, Yuen PW, Zang R, Zhang C, Zhou Y, Zhu X, Quinn JG, Ye X, Kiefer JR, Mao J, Evangelista M, Merchant M, Landry ML, Malhotra S, Purkey HE.   +51 more
europepmc   +1 more source

Stereoselective Synthesis of Glycomimetic Amines From Biomass‐Derived Cyrene

European Journal of Organic Chemistry, EarlyView.
2,3,4‐Trideoxy‐2‐mannosamines, including the unsubstituted one, are accessible as the only endo diastereoisomers by reductive amination of the green solvent Cyrene, derived from pyrolysis of cellulose containing waste biomass. The products are useful chiral synthetic intermediate to nitrogenated glycomimetics.
Debora Pratesi, Marta Rigacci, Francesca Cardona, Camilla Matassini, Andrea Goti   +4 more
wiley   +1 more source

Design principles for enantiospecific <i>para</i>- and <i>ortho</i>-[3,3] rearrangements of chiral aryl-allyl ethers.

Org Chem Front
Breinsperger J, Kaiser M, Gärtner P.
europepmc   +1 more source

Synthesis of 6-<i>epi</i>-Hypersampsone R by a Desymmetrization Strategy. [PDF]

Org Lett
Tariq M, Butcher TW, Virgil SC, Stoltz BM.   +3 more
europepmc   +1 more source

A Route to Annulated Indoles via a Palladium‐Catalyzed Tandem Alkylation/Direct Arylation Reaction.

, 2006
Cyril Bressy, Dino Alberico, Mark Lautens   +2 more
openalex   +2 more sources

Emerging Trends in Organic Photoreactions Utilizing Disulfides

European Journal of Organic Chemistry, EarlyView.
Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar, Bolormaa Bayarkhuu, Hong Y. Cho, Jeehye Byun   +3 more
wiley   +1 more source

Design and Synthesis of Lactose‐Derived Ligands and Their Application in Asymmetric Friedel–Crafts Alkylation

European Journal of Organic Chemistry, EarlyView.
This work describes the synthesis of lactose‐ and glucose‐derived chiral ligands and their application in the catalytic enantioselective Friedel–Crafts alkylation of indole with a series of trans‐β‐nitrostyrenes. The optimal ligand was an acetate protected, lactose‐derived pyridyl imine and its zinc complex afforded ees up to 93% and yields up to 93 ...
Sandra Bulawa, Julia Bruno‐Colmenarez, Patrick J. Guiry   +2 more
wiley   +1 more source