Results 81 to 90 of about 107,279 (237)
Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
The performance of HMCM-22 zeolite catalyst on the olefin alkylation thiophenic sulfur in gasoline
, 2008 The catalytic performance of the HMCM-22 zeolites with different Si/Al-2 ratios for the olefin alkylation thiophenic sulfur (OATS) process was investigated.
Xu Longya +6 more
core +1 more source
Advanced Science, EarlyView.In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong +13 more
wiley +1 more source
Active species in chloroaluminate ionic liquids catalyzing low-temperature polyolefin deconstruction
Nature CommunicationsChloroaluminate ionic liquids selectively transform (waste) polyolefins into gasoline-range alkanes through tandem cracking-alkylation at temperatures below 100 °C.
Wei Zhang +18 more
doaj +1 more source
This thesis describes work completed to expand the scope of hydrogen borrowing enolate alkylation reactions. It was hypothesised that the development of a room temperature reaction would allow utility of a breadth of chemical space previously ...
Bailey, Elliot Peter
core +1 more source
Polarization Engineering in Vinylene‐Linked COFs Toward Efficient Neuromorphic Computing
Advanced Science, EarlyView.A vinyl‐linked covalent organic framework (COF‐DIBPY) was synthesized on a conductive substrate for memristor applications. Redox reactions and bromide migration enable low‐voltage (0.5V) conductance switching with high analog on/off ratio (15.7). The device was further integrated into a speech emotion recognition system for acoustic simulation and ...
Hao Wang +5 more
wiley +1 more source
Shape Selective Alkylation of Biphenyl with 1-octene on ((Al+C3H7Cl)+C2H4) Catalysts [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2003 Alkylation of biphenyl with 1-octene was investigated using ((Al+C3H7Cl)+C2H4) catalysts. The catalytic activity of ((Al+C3H7Cl)+C2H4) for the alkylation was studied at different temperatures, mol ratios of biphenyl to 1-octene, reaction times and ...
Sevil Veli (Veliyeva)
doaj
Ligand Dependent Regioselectivity in Palladium Mediated Allylic Alkylation [PDF]
, 2010 In this thesis, different aspects on ligand dependent regioselectivity in palladium mediated allylic alkylation have been studied. It is believed that the regioselectivity is a result of nucleophilic attack trans to phosphorous when applying ligands ...
Johansson, Charlotte +2 more
core +1 more source
Tungsten-Catalyzed Direct N-Alkylation of Amines with Alcohols [PDF]
, 2020 The implementation of earth-abundant metals mediated chemistry is a major goal in homogeneous catalysis. Borrowing hydrogen/hydrogen autotransfer (BH/HA) reaction, as a straightforward and sustainable synthetic method, has attracted considerable ...
Ming, Huang +6 more
core +1 more source
Advanced Science, EarlyView.This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng +9 more
wiley +1 more source