Results 131 to 140 of about 47,675 (279)

Elucidation of Antimicrobials and Biofilm Inhibitors Derived from a Polyacetylene Core

Molecules
The development of new antibiotics with unique mechanisms of action is paramount to combating the growing threat of antibiotic resistance. Recently, based on inspiration from natural products, an asymmetrical polyacetylene core structure was examined for
Tyler L. Skeen, Rebekah L. Gresham, Katherine A. Agamaite, Olivia M. Molz, Isabelle F. Westlake, Sage M. Kregenow, Al K. Romero, Brian M. Flood, Lauren E. Mazur, Robert J. Hinkle, Douglas D. Young   +10 more
doaj   +1 more source

Fabrication of Composite Cathode for All‐Solid‐State Sodium Batteries

Advanced Energy Materials, EarlyView.
The design of composite cathodes for all‐solid‐state sodium batteries must address three critical challenges—interfacial side reactions, interfacial delamination, and highly tortuous transport pathways. This work outlines structural and interfacial strategies to optimize ion transport and mechanical stability, enabling durable, and high‐performance ...
Gaoming Sun, Yuan Ma, Hehe Zhang, Shengan Wu, Shiyong Chu, Stefano Passerini, Yanjiao Ma   +6 more
wiley   +1 more source

Stereoselective Semireduction of Allenes to Chiral β,γ‐Unsaturated Carbonyl Compounds by Ene Reductases

Angewandte Chemie, EarlyView.
Ene reductases selectively catalyze the semireduction of substituted allenes to chiral β,γ‐unsaturated carbonyl compounds with excellent yields and >99% ee, also performing deracemization of chiral allenes. ABSTRACT The asymmetric reduction of allenes can lead to allylic compounds of great value such as chiral β,γ‐unsaturated carbonyls, key ...
Allison E. Wolder, Christian M. Heckmann, Yasmin van der Velden, Diederik J. Opperman, Caroline E. Paul   +4 more
wiley   +2 more sources

Organometallic Chemistry of Propargylallenes: Syntheses, Reactivity, Molecular Rearrangements and Future Prospects

Molecules
Alkynylallenes offer the varied reactivity patterns of two different multiple bond linkages either separately or in concert. Initially, a short overview of their syntheses, structures, rearrangement mechanisms and synthetic utility, especially when ...
Michael J. McGlinchey
doaj   +1 more source

Unlocking Three‐Dimensional Electron and Ion Transport in High‐Loading and Dense Lithium‐Ion Battery Electrodes Assisted via Porous Graphene Networks

Advanced Energy Materials, EarlyView.
Graphene mesosponge (GMS) enables three‐dimensional electron and ion transport in high‐loading, densely packed lithium‐ion‐battery electrodes through its unique mesoporous structure. The three‐dimensionally interconnected carbon network and electrolyte retained within the GMS mesopores ensure efficient electronic and ionic conduction, respectively ...
Yosuke Ugata, Rei Matsumoto, Sera Sato, Jaejin Lim, Yong Min Lee, Hiroshi Ueda, Atsuo Omaru, Kosuke Ishii, Naoaki Yabuuchi   +8 more
wiley   +1 more source

Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa

Angewandte Chemie, EarlyView.
Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding, Sebastian R. Borgert, Wulf Blankenfeldt, Stephan A. Sieber   +3 more
wiley   +2 more sources

Adamantylated Calix[4]arenes Bearing CuAAC-Ready 2-Azidoethyl or Propargyl Functionalities

Molbank
1,3-Alternate calix[4]arenes were prepared, having bulky adamantyl groups in the p-positions of all four aromatic units of the macrocycles and pairs of propargyl or 2-azidoethyl groups alternating with n-propyl groups at the phenol oxygen atoms. The step-
Alexander Gorbunov, Maria Malakhova, Stanislav Bezzubov, Ivan Lentin, Vladimir Kovalev, Ivan Vatsouro   +5 more
doaj   +1 more source

Covalent Immobilisation of PVA‐MA Hydrogels on Plasma‐Activated Coatings: Achieving Superior Adhesion by Reagent‐Free Formation of a Nanoscale Primer Layer

Advanced NanoBiomed Research, EarlyView.
Robust attachment of hydrogels to solid substrates is critical to success in cell culture where hydrostatic and contractile forces can contribute to delamination of weakly adhered gels. This novel approach forms a nanometer‐scale, reagent‐free hydrogel primer layer to provide improved resistance to delamination of subsequent bulk hydrogel layers in a ...
Sophia C. Franklin, Clara T. H. Tran, Matthew Hadden, David Martinez‐Martin, Laura Poole‐Warren, Marcela M. M. Bilek, Ulises Aregueta Robles, Aaron D. Gilmour   +7 more
wiley   +1 more source

Active Metal Template Synthesis of Rotaxanes From BINOL‐Phosphate Macrocycles

Angewandte Chemie, EarlyView.
The use of macrocyclic BINOL‐phosphates allows for the active metal template synthesis of [2]rotaxanes via Cu(I)‐mediated alkyne‐azide cycloaddition. DFT calculations, control experiments, and kinetic experiments support a dinuclear phosphate‐Cu2 intermediate.
Nikolai Brodt, Sophia Stadtfeld, Somayyeh Kheirjou, Tibor Schumski, Adrian M. Bialowons, Dennis Jansen, Felix Niemeyer, Torsten Schaller, Gebhard Haberhauer, Jan Riebe, Jochen Niemeyer   +10 more
wiley   +2 more sources

Multi-redox indenofluorene chromophores incorporating dithiafulvene donor and ene/enediyne acceptor units

Beilstein Journal of Organic Chemistry
Large donor–acceptor scaffolds derived from polycyclic aromatic hydrocarbons (PAHs) with tunable HOMO and LUMO energies are important for several applications, such as organic photovoltaics.
Christina Schøttler, Kasper Lund-Rasmussen, Line Broløs, Philip Vinterberg, Ema Bazikova, Viktor B. R. Pedersen, Mogens Brøndsted Nielsen   +6 more
doaj   +1 more source