Results 111 to 120 of about 20,013,989 (265)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Predictors of all-cause mortality.

open access: yes, 2018
Predictors of all-cause mortality.
Akshaya Srikanth Bhagavathula (2580460)   +7 more
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Predictors of all-cause mortality.

open access: yes, 2019
Predictors of all-cause mortality.
Sun Ryoung Choi (560113)   +8 more
core   +1 more source

Association of physical activity level and all-cause mortality among stroke survivors: evidence from NHANES 2007–2018

open access: yesEnvironmental Health and Preventive Medicine
Background: Post-stroke disability diminishes the physical activity (PA) level of survivors, potentially affecting their long-term prognosis. This study endeavors to explore the correlation between daily PA level and the all-cause mortality in patients ...
Fude Liu   +7 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Cause-specific contributions to sex differences in adult mortality among whites and African Americans between 1960 and 1995 [PDF]

open access: yes
The purpose of this paper is to describe trends in sex differences in mortality in young adulthood and in middle age among African Americans and whites in the United States between 1960 and 1995.
Greg L. Drevenstedt, Irma Elo
core  

Socioeconomic Inequalities in All-cause and Specific-cause Mortality in Australia: 1985-87 and 1995-97 [PDF]

open access: yes, 2001
Background. Socioeconomic inequalities in mortality have been repeatedly observed in Britain, the United States, and Europe, and in some countries, there is evidence that the differentials are widening.
Mathers, Colin D., Turrell, Gavin
core  

All cause of early mortality.

open access: yes, 2018
All cause of early mortality.
Mohr Rephael (5624645)   +7 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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