Results 91 to 100 of about 20,013,989 (265)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

All-cause mortality according to selected factors.

All-cause mortality according to selected factors.
Cleudson Nery de Castro (11506511), Sheila Cristina Vicente da Silva (18056408), Elizabeth Visone Nunes Westphalen (14108500), Vera Lúcia Teixeira de Freitas (14725433), Christina Terra Gallafrio Novaes (11506502), Fernando Salvador (814802), Maria Aparecida Shikanai-Yasuda (9449009), Renata Buccheri (12051184), Ana Marli Christovam Sartori (10458738), Carolina Bonilla (116077), Rita Cristina Bezerra (17667113), Érika Shimoda Nakanishi (9550085), Caroline Medeji Ramos de Oliveira (3857026), Felipe Delatorre Busser (3856996), Noemia Barbosa Carvalho (3857014), Yeh-Li Ho (6720131)   +15 more
core   +1 more source

All cause mortality.

, 2015
All cause mortality.
Harriet Sommer (795236), Hansjuergen Agostini (795237), Christine M. Schmucker (795235), Christoph Ehlken (145058), Gerta Rücker (50492), Yoon K. Loke (145075), Patrick Oeller (678752), Gianni Virgili (130816)   +7 more
core   +1 more source

Association between isolated minor ST-segment and T wave changes with 10 years all-cause and stroke mortality

Scientific Reports
Minor ST segment and T wave (ST-T) abnormalities are commonly seen on the resting electrocardiograms (ECGs) of healthy individuals, but the long-term effects of these findings, particularly in the general population, have not been thoroughly assessed. As
Sara Saffar Soflaei, Farima Farsi, Alireza Heidari-Bakavoli, Marzieh Kohantorabi, Parsa Mearaji Far, Reza Eftekhar, Reyhaneh Saffar-Khorasani, Habibollah Esmaily, Gordon A. Ferns, Mohesn Moohebati#, Majid Ghayour Mobarhan#, Mohsen Moohebati, Majid Ghayour-Mobarhan   +12 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Unadjusted all-cause mortality.

, 2016
Unadjusted all-cause mortality.
Leonard Kritharides (277594), Vincent Chow (404521), Austin Chin Chwan Ng (404520), David Yuan (2548369), Dona Adikari (2548372), Jerrett K. Lau (2548375), Andy Sze Chiang Yong (404522)   +6 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Sitting-time and 9-year all-cause mortality in older women

, 2015
Background Studies of mid-aged adults provide evidence of a relationship between sitting-time and all-cause mortality, but evidence in older adults is limited.
Pavey, Toby, Pavey, Toby G., Peeters, GMEE (Geeske), Brown, Wendy J., Peeters, Geeske   +4 more
core   +1 more source

30 Year patterns of mortality in Tobago, West Indies, 1976-2005: impact of glucose intolerance and alcohol intake. [PDF]

, 2011
OBJECTIVES: To determine the main predictors of all-cause and cardiovascular (CV) mortality in a rural West Indian population in Plymouth, Tobago over 30 years.
Molokhia Mariam, Molokhia, Mariam, Mariam Molokhia, Paul McKeigue, Nitsch Dorothea, McKeigue, Paul; id_orcid, McKeigue Paul, Patrick, Alan Leslie, Alan Leslie Patrick, McKeigue, Paul, Nitsch, Dorothea, Dorothea Nitsch, Patrick Alan Leslie   +12 more
core   +1 more source