Results 101 to 110 of about 20,013,989 (265)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Marital Partner and Mortality: The Effects of the Social Positions of Both Spouses [PDF]
Background Individual education, social class, social status and income are all associated with mortality, and this is likewise the case for the position of the marital partner.
Torssander, Jenny, Erikson, Robert
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All-cause mortality associated with hyperkalaemia in hospitalised adult patients: a scoping review
African Journal of NephrologyIntroduction: Although the association between hyperkalaemia and all-cause mortality has been described, the evidence for it is fragmented and underrepresents populations from low- and middle-income countries.
Beate Boshoff, Mogamat-Yazied Chothia
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
BMC Pulmonary MedicineBackground Chronic obstructive pulmonary disease (COPD) is viewed as a significant health problem, and the prognosis of patients with this disease is strongly influenced by the inflammatory response and nutritional well-being of the body.
Zhuanbo Luo +4 more
doaj +1 more source
Risk Management and Healthcare Policy, 2020 Chao-lei Chen,1,* Lin Liu,1,* Jia-yi Huang,1 Yu-ling Yu,1 Geng Shen,1 Kenneth Lo,1,2 Yu-qing Huang,1 Ying-qing Feng1 1Department of Cardiology, Hypertension Research Laboratory, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention ...
Chen C +7 more
doaj
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Are Alcohol Excise Taxes Good For Us? Short and Long-Term Effects on Mortality Rates [PDF]
Regression results from a 30-year panel of the state-level data indicate that changes in alcohol-excise taxes cause a reduction in drinking and lower all-cause mortality in the short run.
Philip J. Cook +2 more
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