Results 41 to 50 of about 611 (135)
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui +12 more
wiley +1 more source
Lipid Nanoparticles in Drug Delivery: Overcoming Challenges and Unlocking New Frontiers
Lipid nanoparticles (LNPs) have revolutionized nucleic acid delivery, yet challenges in formulation, stability, and targeted efficacy persist. This review explores how advances in microfluidic manufacturing, precision targeting, and endosomal escape are reshaping LNP design.
Jordan Kambanis +7 more
wiley +1 more source
Device uncertainty propagation in low-ductility RC frames retrofitted with BRBs for seismic risk mitigation [PDF]
Passive control systems, such as buckling-restrained braces (BRBs), have emerged as efficient tools for seismic response control of new and existing structures by imparting strength and stiffness to buildings, while providing additional high and stable ...
Freddi, F +3 more
core
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck +4 more
wiley +1 more source
The environmental behavior and impact of anti‐corrosion nanoadditives, ZnAl‐NO2 and MgAl‐NO2 layered double hydroxides (LDH), are assessed under marine conditions. These nanomaterials show instability in water but exhibit no or low toxicity to most tested marine species.
Joana Figueiredo +12 more
wiley +1 more source
Numerical Investigation of Seismic Response of Hybrid Buckling Restrained Braced Frames [PDF]
The Conventional buckling restrained braces used in concentrically braced frames are expected to yield in both tension and compression without major degradation of capacity under severe seismic ground motions.
Hoveidae, Nader
core +1 more source
Influence of the design objectives on the seismic performance of steel moment resisting frames retrofitted with buckling restrained braces [PDF]
Buckling restrained braces (BRBs) represent an effective strategy for the seismic retrofit of existing steel moment resisting frames (MRFs), as they contribute to increasing the strength and ductility capacity of the structure.
Freddi, Fabio +1 more
core
ABSTRACT Cognitive impairment is a common symptom of multiple sclerosis (MS) and has a substantial impact on quality of life (QoL). In Japan, cognitive assessment has traditionally lagged behind that in Western countries. With the emerging concept of smoldering‐associated worsening, the importance of longitudinal cognitive monitoring is becoming ...
Shuka Okuda, Juichi Fujimori
wiley +1 more source
Damage Avoidance Design of Special Truss Girder Frames with Energy Dissipation Devices [PDF]
An innovative detail that facilitates the use of energy dissipating devices, such as Buckling Restrained Braces (BRBs), is proposed for Special Truss Moment Frames (STMFs).
Linke, Christin
core +1 more source

