Results 31 to 40 of about 15,723,400 (130)

Glucose Transporter 1 in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai   +3 more
wiley   +1 more source

Sensitivity-based model updating of steel frames with BRBs in OpenSees

open access: yes, 2015
Response sensitivities for an elastoplastic model specifically developed for buckling-restrained braces (BRBs) and recently implemented in OpenSees, are used as a tool for model updating of steel frames with BRBs.
ZONA, Alessandro   +3 more
core   +1 more source

Infection control in the brain and the eye

open access: yesActa Ophthalmologica, Volume 104, Issue 5, Page e478-e490, August 2026.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester   +2 more
wiley   +1 more source

Current Landscape and Future Perspectives of Diabetic Retinopathy Therapy: Pharmacological Targets, Precision Laser Technology, and Clinical Evidence

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Targeted biological agents targeting VEGF, integrin, dopamine D2 receptor, ROCK, and BCL‐XL have entered the clinical trial phase and deserve particular attention. The treatment paradigm has shifted toward personalized and precision medicine, positioning optimized SML as a promising adjunctive therapy.
Xinying Hu   +7 more
wiley   +1 more source

"All-steel" buckling-restrained braces for seismic upgrading

open access: yes, 2015
Buckling-Restrained Braces (BRBs) constitute a significant advancement over traditional seismic-resistant bracing systems. Multiple applications are possible, from seismic protection of new and modern steel buildings to their utilization as hysteretic ...
D'ANIELLO, MARIO   +3 more
core  

Proteolytic remodelling of the extracellular matrix by pericytes

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard   +4 more
wiley   +1 more source

Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles

open access: yesEuropean Journal of Immunology, Volume 56, Issue 6, June 2026.
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes   +2 more
wiley   +1 more source

Fragility Analysis of Concrete-Filled Steel Tubular Frame Structures with BRBs under Multiple Earthquakes Considering Strain Rate Effects

open access: yes, 2019
The fragility of concrete-filled steel tubular (CFST) frame structures with buckling-restrained braces (BRBs) subjected to multiple earthquakes is studied in this paper.
Hao Zhang   +4 more
core   +1 more source

Careers with Bethlehem Steel: and the Loop Course

open access: yes, 1955
This book discusses the career opportunities for college men seeking employment with in the Bethlehem Steel Company. Specifically the book discusses the Bethlehem Loop Course, which was established to give employees straight out of college the ...

core  

Overall Buckling Behavior of All-Steel Buckling Restrained Braces [PDF]

open access: yes, 2012
One of the key requirements for the desirable mechanical behavior of buckling restrained braces (BRBs) under earthquake loading is to prevent global buckling until the brace member reaches sufficient plastic deformation and ductility. This paper presents
Hoveidae, Nader, Rafezy, Behzad
core   +1 more source

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