Results 21 to 30 of about 15,723,400 (130)

FOXO6 inhibits SMURF2‐mediated ubiquitination and degradation of NR4A1 to promote retinal pigment epithelial cell ferroptosis in diabetic retinopathy

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
FOXO6 suppresses the transcriptional expression of SMURF2, thereby limiting the ubiquitination and degradation of NR4A1. Stabilized NR4A1 promotes ferroptosis in RPE cells, contributing to the progression of diabetic retinopathy. Abstract Diabetic retinopathy (DR) is the main cause of vision loss, with retinal pigment epithelial (RPE) cell dysfunction ...
Qiao Chen, Bo Su, Ke Xu, Liang Li, Changzheng Chen   +4 more
wiley   +1 more source

Hysteretic Behavior Of Steel Core Buckling Restrained Brace (brbs) And Design Of A Steel Building Incorporating Brbs [PDF]

, 2013
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2013Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2013Bu çalışma, Burkulması Önlenmiş Çapraz ın (BÖÇ) kuramsal olarak incelenmesini ve ...
Çetinkaya, Seçkin
core  

Evaluation of Component‐Based Finite Element Method for Seismic Bracing Connections in Buckling‐Restrained Braced Frames designed according to AISC Provisions

ce/papers, Volume 9, Issue 2-3, Page 2554-2560, September 2026.
Abstract This paper evaluates the applicability of the Component‐Based Finite Element Method (CBFEM) for seismic verification of bracing connections in Buckling‐Restrained Braced Frames (BRBFs) designed according to AISC 341‐16 and AISC 360‐16. Two representative proprietary CoreBrace bracing configurations—Chevron and Corner bolted brace‐to‐gusset ...
Mustafa Mahamid, Satyam Bhosale, Martin Vild   +2 more
wiley   +1 more source

Experimental Investigation of Timber Buckling‐Restrained Braces under Cyclic Loading

ce/papers, Volume 9, Issue 2-3, Page 1207-1213, September 2026.
Abstract This paper presents the results from an experimental investigation of the hysteretic behaviour of a novel‐developed class of timber‐buckling‐restrained bracings (T‐BRBs). The proposed system, which has been evaluated with and without an external steel tube, consists of a steel core and an oak mass timber casing.
Nima Pahlavannejad Tabarestani, Stephen J. Hicks, Rodrigo de Moura Gonçalves   +2 more
wiley   +1 more source

Comparative Study of Optimally Designed Hybrid Steel‐Timber Coupled Shear Wall Systems

ce/papers, Volume 9, Issue 2-3, Page 1159-1164, September 2026.
Abstract Hybrid timber‐based structural systems are increasingly adopted in high‐seismic regions, where cross‐laminated timber (CLT) coupled wall (CW) systems provide efficient lateral resistance. This study compares optimally designed CLT–CW systems employing conventional steel link beams (SLBs) and diagonally arranged buckling‐restrained braces (BRBs)
Kazuma Hayashida, Cristiano Loss, Yuji Miyazu   +2 more
wiley   +1 more source

EXPERIMENTAL STUDY ON THE LATERAL THRUST GENERATED BY CORE BUCKLING IN BOLTED-BRBs

, 2016
The paper presents the results of cyclic loading tests on all-steel buckling-restrained braces (BRBs), with the aim of investigating the contact phenomena and the associated lateral thrust occurring when the inner core of a BRB, after buckling, comes ...
BREGOLI, Guido, METELLI, Giovanni, GENNA, Francesco   +2 more
core   +1 more source

Seismic retrofitting of steel MRFs with external BRBs: preliminary experimental and numerical results [PDF]

The use of buckling-restrained braces (BRBs) represents an effective retrofit strategy to significantly improve the seismic performance of existing structures.
D’Aniello, Mario, Stathas, Nikolaos, Landolfo, Raffaele, Di Sarno, Luigi, Cicia, Massimo, Gutiérrez-Urzúa, Luis Fernando, Wu, Jingren, Bousias, Stathis, Kwon, Oh-Sung, Park, Jamin, Strepelias, Elias, Freddi, Fabio   +11 more
core   +1 more source

Cascade‐targeted intervention of the NLRP3 inflammasome and downstream angiogenesis by curcumin nanoparticles for ocular neovascularization therapy

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Ultrasound‐microreactor synthesizes monodisperse 125 nm Cur‐NPs with enhanced solubility. Cur‐NPs suppress VEGF signaling and retinal neovascularization via the NLRP3 axis. Multi‐omics profiling reveals that Cur‐NPs reprogram retinal microglia and metabolic pathways.
Siyu Jiang, Ziwei Cheng, Yujuan Cai, Yanji Zhu, Nyamjargal Nyambayar, Ruijie Lin, Li Zhang, Jian Chen, Bing Xie, Xiuping Chen   +9 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Full‐scale Shaking Table Tests on a 10‐story Steel Moment‐resisting Frame Building with Buckling‐restrained Braces

Earthquake Engineering &Structural Dynamics, Volume 55, Issue 10, Page 2356-2378, August 2026.
ABSTRACT In February 2023, a comprehensive series of shaking table tests were conducted at the E‐Defense facility, the world's largest three‐dimensional earthquake simulator, on a full‐scale 10‐story steel moment‐resisting frame supplemented with BRBs.
Jun Fujiwara, Jialiang Jin, Jionghui Li, Tianhao Yan, Ryota Nishi, Akiko Kishida, Koichi Kajiwara, Takuya Nagae, Taichiro Okazaki, Tatsuya Asai   +9 more
wiley   +1 more source