Results 221 to 230 of about 1,408,208 (397)

VARIEGATION INITIATED BY A DOMINANT ALLELE IN THE TOMATO [PDF]

, 1963
Margaret Mann Lesley, J. W. Lesley, R. K. Soost   +2 more
openalex   +1 more source

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

Nature, 1991
K. Falk, O. Rötzschke, Stefan Stevanovié, G. Jung, H. Rammensee   +4 more
semanticscholar   +1 more source

Fc Proteoforms of ACPA IgG Discriminate Autoimmune Responses in Plasma and Synovial Fluid of Rheumatoid Arthritis Patients and Associate with Disease Activity

Advanced Science, EarlyView.
Rheumatoid arthritis is a prototypic autoimmune disease characterized by highly prevalent autoantibodies – anti‐citrullinated protein antibodies (ACPA). A novel nanoHPLC‐MS approach based on the intact Fc/2 subunit identifies hitherto neglected Fc proteoform profiles of IgG (auto)antibodies across different biofluids. The findings demonstrate subclass‐
Constantin Blöchl, Eva Maria Stork, Hans Ulrich Scherer, Rene E. M. Toes, Manfred Wuhrer, Elena Domínguez‐Vega   +5 more
wiley   +1 more source

THE DESCRIPTION OF GENE ACTION AND INTERACTION WITH MULTIPLE ALLELES IN CONTINUOUS VARIATION [PDF]

, 1965
P. Narain
openalex   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Allele [PDF]

, 2011
openaire   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

The Thai variant and the distribution of alleles of 6-phosphogluconate dehydrogenase and the distribution of glucose 6-phosphate dehydrogenase deficiency in Thailand [PDF]

, 1968
Soodsarkorn Tuchinda, Donald L. Rucknagel, S Na-Nakorn, Prawase Wasi   +3 more
openalex   +1 more source

Allelism

Cold Spring Harbor Symposia on Quantitative Biology, 1956
openaire   +2 more sources

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

Advanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng, Xuegang Wang, Mingjun Zhong, Jia Geng, Wenjian Li, Kanglu Pei, Jing Wang, Lanchen Wang, Yu Lu, Jing Cheng, Fengxiao Bu, Huijun Yuan   +11 more
wiley   +1 more source