Results 241 to 250 of about 1,186,851 (331)

Generation of Mice Harboring Bicc1 Conditional Null Alleles. [PDF]

Genesis
Liu CF, Leon S, Herrig I, Wessely O, Tang WHW.   +4 more
europepmc   +1 more source

Evolutionary Divergence of an Ethylene‐Responsive Transcriptional Cascade Governs a Dose‐Dependent Balance between Cotton Fiber Length and Strength

Advanced Science, EarlyView.
A tunable, ethylene‐responsive cascade governing the dose‐dependent balance between fiber length and strength is unveiled. Elevated ethylene strengthens modern tetraploid cotton (G. hirsutum) fibers but elongates those of its diploid ancestor (G. arboreum). This phenotypic switch is traced to an evolutionary functional inversion of a conserved EIN3‐ERF‐
Jie Zhang, Mengli Yu, Yuling Guo, Jie Li, Gailing Gu, Ghulam Hussain, Shuya Ma, Fuguang Li, Hongwei Xue, Zhaoen Yang, Zuoren Yang   +10 more
wiley   +1 more source

Missing or Mis-Telling the Story? Trade-Offs for Restriction-Site Associated Compared to Whole Genome Sequencing. [PDF]

Mol Ecol
Atsawawaranunt K, Stuart KC, Whibley A, Ewart KM, Rollins LA, Johnson RN, Santure AW.   +6 more
europepmc   +1 more source

ELECTROMORPHS OR ALLELES? [PDF]

Genetics, 1977
openaire   +2 more sources

Uncoupling Metastasis and Epithelial‐to‐Mesenchymal Transition in sgP19/kRAS‐Driven Spontaneous Metastatic Liver Tumor Model

Advanced Science, EarlyView.
The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang, Zijing Xu, Lei Xu, Lishan Wang, Jiahao Geng, Xue Wang, Meng Xu, Daphne Superville, Melissa Reeves, Matthias Evert, Diego F. Calvisi, Xin Chen, Xinhua Song   +12 more
wiley   +1 more source

Association of IL28B Polymorphisms With Hepatitis C Susceptibility in Southern Iran's β-Thalassemia Population: A Cross-Sectional Study. [PDF]

Health Sci Rep
Askari F, Kargar M, Deris Zayeri Z, Jalalifar MA, Keikhaei B, Kaydani GA.   +5 more
europepmc   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

rs9789446 genotype as susceptibility biomarkers for congenital hypothyroidism based on population and family validation. [PDF]

Front Genet
Zhong X, Jia Y, Liu W, Qiao M, Li M, Yu X, Liu S.   +6 more
europepmc   +1 more source

Additional file 1: Table S1. of Population differentiation in allele frequencies of obesity-associated SNPs

, 2017
Linyong Mao, Ya-Yin Fang, Michael C. Campbell, William M. Southerland   +3 more
openalex   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source