Results 21 to 30 of about 1,486,266 (226)

Assessment of Haptoglobin 2-2 Genotype in Type 2 Diabetes and Cardiovascular Patients in North Indian Population: A Case-control Study [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Haptoglobin (Hp), an acute phase protein, is a plasma inflammatory marker. It is important in both infectious and non infectious illnesses.
Puneet, Atul Kumar Upadhyay, Manpreet Kaur, Rattan Deep Singh   +3 more
doaj   +1 more source

Assortative human pair-bonding for partner ancestry and allelic variation of the dopamine receptor D4 (DRD4) gene [PDF]

, 2008
The 7R allele of the dopamine receptor D4 gene has been associated with attention-deficit hyperactivity disorder and risk taking. On the cross-population scale, 7R allele frequencies have been shown to be higher in populations with more of a history of ...
Anna Dreber, Asghari, Benjamin C. Campbell, Boom, Coren L. Apicella, Dan T. A. Eisenberg, Eisenberg, Feigelson, Gal, Hutchison, J. Koji Lum, Justin R. Garcia, Lucentini, Matsumoto, Rebollo, Watts   +15 more
core   +3 more sources

RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletes [PDF]

, 2014
Context: The RANK/RANKL/OPG signalling pathway is important in the regulation of bone turnover, with single nucleotide polymorphisms (SNPs) in genes within this pathway associated with bone phenotypic adaptations.
Albagha, Beilin, Bennell, Bone, Boyle, Chatzipapas, Collin-Osdoby, Cosman, Craig Ranson, Craig Sale, Davenport, David C. Hughes, Ekstrand, Fyhrie, Gaeta, Garnero, Guo, Hegedus, Ian Varley, Iwamoto, Julie P. Greeves, Korvala, Lambros, Lappe, Loud, Milner, Paternoster, Paternoster, Paternoster, Ranson, Richards, Roshandel, Roshandel, Scott, Scott, Styrkarsdottir, Tenforde, Trent Stellingwerff, Van Meensel, Wakamatsu, Walsh, Warden, West, William D. Fraser, Yanovich, Yoskovitz   +45 more
core   +1 more source

Wxlv, the Ancestral Allele of Rice Waxy Gene

Proceedings, 2020
In rice endosperms, the Waxy (Wx) gene is important for amylose synthesis, and various Wx alleles control the amylose content and affect the taste of cooked rice.
Changquan Zhang, Jihui Zhu, Shengjie Chen, Qiaoquan Liu   +3 more
semanticscholar   +1 more source

Characterizing allele- and haplotype-specific copy numbers in single cells with CHISEL

Nature Biotechnology, 2020
Single-cell barcoding technologies enable genome sequencing of thousands of individual cells in parallel, but with extremely low sequencing coverage (
Simone Zaccaria, Benjamin J. Raphael
semanticscholar   +1 more source

Brief communication: Evolution of a specific O allele (O1vG542A) supports unique ancestry of Native Americans [PDF]

, 2013
In this study, we explore the geographic and temporal distribution of a unique variant of the O blood group allele called O1vG542A, which has been shown to be shared among Native Americans but is rare in other populations.
, , , Achilli, Acuna-Alonzo, Bolnick, Bortolini, Campbell, Chester, Crawford, Dulik, Dulik, Eshleman, Estrada-Mena, Fagundes, Fagundes, Gagneux, Gardner, Georges, Greenberg, Halverson, Hummel, Hunemeier, Johnson, Jurmain, Karafet, Karafet, Karafet, Kemp, Kemp, Kemp, Kitchen, Lell, Lell, Llop, Malhi, Molnar, Mourant, Mulligan, Nichols, Perego, Perego, Reich, Schroeder, Schroeder, Schurr, Smith, Swerdlow, Szathmary, Tamm, Underhill, Vajda, Yip, Yip, Yip, Zegura   +55 more
core   +4 more sources

Warmblood fragile foal syndrome type 1 mutation (PLOD1 c.2032G>A) is not associated with catastrophic breakdown and has a low allele frequency in the Thoroughbred breed. [PDF]

, 2020
BackgroundCatastrophic fractures are among the most common cause of fatalities in racehorses. Several factors, including genetics, likely contribute to increased risk for fatal injuries.
Arthur, R, Bellone, RR, Finno, CJ, Hughes, SS, Le, V, Ocampo, NR, Penedo, MCT   +6 more
core   +1 more source

Single-cell RNA counting at allele and isoform resolution using Smart-seq3

Nature Biotechnology, 2019
Large-scale sequencing of RNA from individual cells can reveal patterns of gene, isoform and allelic expression across cell types and states1. However, current short-read single-cell RNA-sequencing methods have limited ability to count RNAs at allele and
M. Hagemann-Jensen, C. Ziegenhain, Ping Chen, D. Ramsköld, Gert-Jan Hendriks, Anton J. M. Larsson, O. Faridani, R. Sandberg   +7 more
semanticscholar   +1 more source

Alcohol-related expectancies are associated with the D2 dopamine receptor and GABAa receptor B3 subunit genes [PDF]

, 2004
Molecular genetic research has identified promising markers of alcohol dependence, including alleles of the D2 dopamine receptor (DRD2) and the GABAA receptor ￢3 subunit (GABRB3) genes.
Bandura, Bandura, Bau, Berman, Berridge, Blomqvist, Blum, Bruce R Lawford, Christiansen, Cohen, Comings, Connor, Connor, David, Davies, Depue, DiChiara, DiChiara, DiChiara, DiChiara, Dimitrov, Duan, Dudek, Ernest P Noble, Feeney, Gelernter, Gerald F.X Feeney, Goldman, Grandy, Greenfield, Gurling, Hitzemann, Hollerman, Ikemoto, Jönsson, Kidd, Knight, Laruelle, Lawford, Lawford, Lawford, Lawford, Long, Luddens, Madrid, Maldonado, McCarthy, McCarthy, Miller, Monti, Mutirangura, Neiswanger, Noble, Noble, Noble, Noble, Noble, Noble, Noble, Noble, Noone, Ott, Pato, Persico, Pohjalainen, Robinson, Ross McD Young, Schultz, Schultz, Selzer, Silvestri, Spitz, Terry Ritchie, Thanos, Thompson, Uhl, Vernon, Vik, Volkow, Volkow, Wells-Parker, Williams, Wilson, Wise, Young, Young, Young, Young   +87 more
core   +2 more sources

FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing

Nucleic Acids Research, 2016
Allele-specific copy number analysis (ASCN) from next generation sequencing (NGS) data can greatly extend the utility of NGS beyond the identification of mutations to precisely annotate the genome for the detection of homozygous/heterozygous deletions ...
R. Shen, V. Seshan
semanticscholar   +1 more source